Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Blood Stem Cell Transplantation

Blood Stem Cell Transplantation

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781461563495
Condition
New
Product Description

Blood Stem Cell Transplantation conveys the excitement that accompanies the newest developments in hematopoietic stem cell transplantation. Some of the applications that stand to impact this field most significantly are based on recent advances in the biological sciences, as demonstrated by the chapters on gene therapy, on the detection of minimal residual disease using molecular techniques, and on the use of radioimmunoconjugates targeting lymphoma and leukemia-associated antigens. Others are the results of clinical observations - e.g., the association between graft-versus-host- disease (GVHD) and durable remissions that have led to creative clinical experiments such as donor leukocyte infusions (DLI). Attempts to unravel the biological events that underlie the responses seen in patients with relapsed chronic myelogenous leukemia treated with DLI are likely to provide the basis for future refinements in this clinical approach. Hopefully, improved response rates and reduced toxicity will result. The power of the immunologic response in controlling malignant disease is underscored in the chapter on post-transplant immunotherapy. The complex immunologic process that results in clinical GVHD may be dissected and engineered to provide clinical benefits that include, in addition to its antineoplastic effects, the amelioration of its clinical manifestations. Better control of GVHD with less global immunosuppression will facilitate the use of mismatched and unrelated donors. This area of investigation perfectly illustrates the continued interplay between the laboratory and the clinic. The continued cross-fertilization of ideas between immunologists, molecular biologists and clinical investigators is likely to yield important advances in this field for years to come. Possible applications of stem cell transplantation continue to grow with the identification of alternative sources of stem cells and the potential to engineer and/orexpand the graft. Although the use of unrelated and mismatched donors continues to increase, the possibilities associated with umbilical cord blood transplantation are legion, especially if stem cells can be expanded ex vivo to provide grafts for full-sized adults. Using techniques in which contaminating malignant cells may be eliminated from autografts through positive selection, autologous transplantation may prove highly effective, especially when coupled with post-transplant immunotherapy. Some of these same methodologies have helped facilitate the use of autologous grafts for transplantation in patients with chronic myelogenous leukemia without allogeneic donors. Advances in the supportive care of transplant patients, including the pretransplant identification of those at risk from pulmonary complications and the use of cytokines to speed engraftment, have reduced morbidity and mortality to such a degree that it is appropriate to consider high-dose therapy and stem cell reconstitution in patients with nonmalignant diseases. The impressive advances that have occurred in transplantation for thalassemia are described by pioneers in their area of investigation. The burgeoning field of transplantation for autoimmune disorders, including its immunobiologic basis and soon-to- be-realized clinical potential, is also summarized. Continued progress in the use of high-dose therapy with stem cell rescue for the treatment of pediatric tumors, which derives in part from improved supportive care, is detailed. The sobering voice of the health care economists underscores the necessary limitations to our seemingly unbridled imagination. Cost- consciousness and financial know-how will need to be reflected in future study designs. Given the seemingly endless applications of our technology, strategies to insure its cost-effectiveness will be necessary. Continued financial support for laboratory investigation and for the clinical experiments they generate will be required if we are to go forward. Blood Stem Cell Transplantation lays the foundation for many of these future advances; it is incumbent upon us all to insure its realization.

Available Colors
Available Sizes
1 Offer Price Range: $259.00 - $259.00
BEST PRICE

Single Product Purchase

$259.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$259.00 $259.00

$259.00
See Site In stock Visit Store

Similar Products

Medicine and Business

$79.99

Revisionsendoprothetik der Hftpfanne

$99.99

Diskriminierungs- und Rassismuserfahrungen im Schulwesen

$74.99

Multi-Frame Motion-Compensated Prediction for Video Transmission

$129.00

The Supercontinuum Laser Source

$149.00

Ultimate Read-Aloud Collection Grade 5

$578.00

Die Liberalisierung des britischen Telekommunikationsmarktes

$69.99

The Physics of Hydrogenated Amorphous Silicon II

$39.99

Die Eingriffe bei den Bauchbrchen

$44.99

Chemical and Biological Warfare

$44.99

Practical Guide to Patch Testing

$69.99

Major Energy Companies of Europe 1994

$74.99

Wired/Wireless Internet Communications

$39.99

Scrum - Einfhrung in der Unternehmenspraxis

$39.99

Genetic Responsibility

$54.99

Gewinnungsarbeiten, Wasserhaltung

$59.99

Active Probe Atomic Force Microscopy

$99.99

Science of Cyber Security

$39.99

Clifford the Big Red Dog: Clifford's Happy Easter

$5.24

Successful Case-based Reasoning Applications-2

$84.99

Mechanics in Structural Geology

$54.99

The Reshaping of China-Southeast Asia Relations in Light of the COVID-19 Pandemic

$99.00

The Role of Solar Ultraviolet Radiation in Marine Ecosystems

$39.99

Knowledge and Technology Transfer for Plant Pathology

$169.99

Fairies, Demons, and Nature Spirits

$159.99

The Skadar/Shkodra Lake Environment

$299.00

Distributed Fuzzy Control of Multivariable Systems

$109.99

SAP SuccessFactors Talent: Volume 2

$79.99

Writing Constitutions

$119.99

Geometric and Topological Methods for Quantum Field Theory

$84.99

The History of Medical Informatics in the United States

$54.99

What If You Had Animal Hair!?

$2.99

Las mujeres de la Biblia nos hablan: La sabiduria de 16 mujeres y sus lecciones para hoy / The Women of the Bible Speak by Shannon Bream

$15.99

Look & Find at School (Hardcover)

$7.46

Disseminating Security Updates at Internet Scale

$84.99

Kalman-Filter

$29.99

Biogas Methangrung organischer Abfallstoffe

$59.99

Martin Heidegger: In Europe and America

$109.99

The Inspiration Motif in the Works of Franz Grillparzer

$109.99

My Books Every Day Self-Awareness Grade 2-Classroom Set

$636.95