Copied Viral Proteins Counteracting Host Defenses
Viral Proteins Counteracting Host Defenses
Since the first observations of viral interference with antigen presentation in the MHC class-I pathway, the field has advanced to a detailed analysis. We know numerous genes and for some of them we have profound information on their mechanistic function. The antigen presentation pathway is affected at all stages starting from proteasomal degradation of an antigenic viral protein, as shown for EBV, transfer of the proteasomal cleavage products as peptides in the ER by specific transporters, the loading of the nascent MHC class-I molecule, and finally the transport of the complex to the surface and presentation in a normal or deranged form. All these different steps of the MHC class-I antigen presentation pathway are targets for viral proteins. Not only MHC class-I but also MHC class-II proteins are a target of viral influence either by direct downregulation and degradation of proteins or by interference of signal transduction pathways.
Price Comparison
| Seller | Contact Seller | List Price | On Sale | Shipping | Best Promo | Final Price | Volume Discount | Financing | Availability | Seller's Page |
|---|---|---|---|---|---|---|---|---|---|---|
|
BEST PRICE 1 Product Purchase
|
|
$84.99 | $84.99 |
|
$84.99 | See Site | In stock | Visit Store |
Reviews
Questions & Answers
Managerial Uses of Accounting Information
$109.99
Foundations of Genetic Programming
$109.99
Sesame Street: Guess Who, Elmo! by Wendy Wax
$10.99
Patterns of Growth and Development in Cattle
$54.99
Grundfragen der betrieblichen Personalpolitik
$44.99
Field Emission in Vacuum Microelectronics
$84.99
Bacterial Molecular Networks
$219.99
The Scholar and the State: In Search of Van der Waerden
$119.99
Smart Internet of Things for Environment and Healthcare
$219.99
Schmelzgleichgewichte im System Eisen-Schwefel-Kohlenstoff-Phosphor und Silizium bei 1400C
$54.99
VDM '91. Formal Software Development Methods. 4th International Symposium of VDM Europe, Noordwijker
$39.99
Genetics and the Electroencephalogram
$109.99
Tumors of the Central Nervous System, Volume 13
$129.00
Time in Quantum Mechanics - Vol. 2
$39.99
Special Topics in Multimedia, IoT and Web Technologies
$199.99
Fuzzy Cognitive Maps for Applied Sciences and Engineering
$109.99
Coalition Formation and Social Choice
$109.99
Die Berechnung der Zylinderschalen
$44.99
Environmental Science - A Ground Zero Observation on the Indian Subcontinent
$129.00
Ceramic Processing
$169.99
How to Avoid Extinction
$5.24
Shakespeares Foreign Queens
$84.99
Nichtwissen strt mich (nicht)
$44.99
Algorithms - ESA 2000
$39.99
Economics of Grids, Clouds, Systems, and Services
$54.99
Freedom Swimmer (Hardcover)
$14.24
Reaganomics Goes Global
$109.99
Molekulardynamik
$34.99
Fostering Trade in Africa
$139.00
Toeplitz-Quantisierung symmetrischer Gebiete auf Grundlage der C*-Dualitt
$74.99
Good Housekeeping Slow Cooker - Quick-Prep Recipes by Susan Westmoreland
$16.95
The Limbic System
$54.99
Die Produktion von Diversitt in stdtischen Verwaltungen
$39.99
Turbo Pascal fr Ingenieure
$69.99
Electromagnetic Scattering in Disperse Media
$169.99
Differential Equations
$1.85
Fruit Processing
$169.99
Regulation of the Power Sector
$329.99
Soft Errors in Modern Electronic Systems
$129.00
Transactions of the International Astronomical Union, Volume XVIIB
$219.99
