Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Cancer Biology and the Nuclear Envelope

Cancer Biology and the Nuclear Envelope

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781489980328
Condition
New
Product Description

"Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer.".

Available Colors
Available Sizes
1 Offer Price Range: $169.00 - $169.00
BEST PRICE

Single Product Purchase

$169.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$169.00 $169.00

$169.00
See Site In stock Visit Store

Similar Products

Quantitative Methods in Proteomics

$109.99

Mechanical Integration of Plant Cells and Plants

$169.99

Cancer Proteomics

$169.00

Santz-Multiplikator D.R.G.M

$49.99

Ecosystems

$14.95

William Corder and the Red Barn Murder

$54.99

Neonatal Kidney and Fluid-Electrolytes

$219.99

Adsorption on Ordered Surfaces of Ionic Solids and Thin Films

$109.99

Kinder- und Jugendmedizin

$69.99

Dickwerden und Schlankbleiben

$59.99

Molecular Sensors for Cardiovascular Homeostasis

$169.99

Disaster Risk Science

$169.99

Climate and Geo-Sciences

$219.99

Nondestructive Testing of Materials and Structures

$549.99

Plague-Making and the AIDS Epidemic: A Story of Discrimination

$54.99

Chaostheorie und Unternehmenssteuerung

$69.99

Developmental Instability: Its Origins and Evolutionary Implications

$219.99

The Neurophysiological Bases of Auditory Perception

$169.00

Handbuch der Baugeologie und Geotechnik

$229.99

Pro WPF in VB 2010

$39.99

Gerichtliche Medizin

$129.99

Das Prfungsbuch

$29.99

ICT for Engineering & Critical Infrastructures

$149.00

Sustainable Tunneling and Underground Use

$109.99

Volkswirtschaftslehre mathematisch gedacht

$39.99

The Disoriented State

$109.99

The Best Me I Can Be: lo que debo hacer

$3.71

Overcoming Isolation

$84.99

The Cloud DBA-Oracle

$44.99

The Opioid Epidemic and the Therapeutic Community Model

$139.99

Der Schlssel zum indischen Markt

$34.99

Praktische Baustatik

$64.99

Ghost Hunt

$6.71

Scale Structure Formation

$109.99

Grundri einer Meteorobiologie des Menschen

$59.99

Security, Privacy and Trust in Cloud Systems

$109.99

Computer und Produktivitt

$44.99

Computational Intelligence, Communications, and Business Analytics

$89.99

Presidents, Prime Ministers and Chancellors

$54.99

YSEC Yearbook of Socio-Economic Constitutions 2020

$199.99