Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Drug Transporters in Drug Disposition, Effects and Toxicity

Drug Transporters in Drug Disposition, Effects and Toxicity

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9789811376474
Condition
New
Product Description

This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Transporters are known determinants of drug disposition and efficacy/toxicity. In general, they are divided into solute carrier (SLC) and ATP binding cassette (ABC) families, and are located along cell membranes, where they mediate drug uptake into cells and export out of cells. Drug transporters are essential in maintaining cell homeostasis, and their gene mutations may cause or contribute to severe human genetic disorders, such as cystic fibrosis, neurological disease, retinal degeneration, anemia, and cholesterol and bile transport defects. Conversely, some diseases may also alter transporter functions and expressions, in turn aggravating disease process. Further, since over-expression of some ABC transporters is a potential contributor to multidrug-resistance (MDR), the book presentsa number of strategies to overcome MDR, including ABC transporter inhibitors and applying epigenetic methods to modulate transporter expressions and functions. This book is useful for graduate students and professionals who are looking to refresh or expand their knowledge of this exciting field.

Available Colors
Available Sizes
1 Offer Price Range: $169.00 - $169.00
BEST PRICE

Single Product Purchase

$169.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$169.00 $169.00

$169.00
See Site In stock Visit Store

Similar Products

Medien und Musik

$9.99

Neuer intuitiver Zugang zum strukturalistischen Theorienkonzept. Theorie-Elemente. Theoriennetze. Th

$29.99

FORTRAN IV/77-Programm zur Finite-Elemente-Methode

$69.99

Nineteenth Century Premiers

$54.99

Fuzzy Stochastic Multiobjective Programming

$84.99

El poder del monstruo: A Branches Book (El autobs mgico vuelve a despegar)

$3.74

Professionalizing Your English Language Teaching

$89.99

(In)Visible Presence: Feminist Counter-narratives of Young Adult Literature by Women of Color

$49.99

Dermatological Manifestations of Kidney Disease

$84.99

Geistig fit ins Alter

$54.99

Anstze zu einer quantitativen Theorie der Konzertierten Aktion

$59.99

Topology and Geometry in Polymer Science

$109.99

Storyboarding

$119.00

Hybrid and Real-Time Systems

$39.99

ROR Exclusive: Jabari Tries Case Pack

$292.50

Bewegung in der frhen Kindheit

$79.99

Franz Rosenzweigs Philosophy of Existence

$54.99

Journalismus in der digitalen Moderne

$29.95

Organic Fluorine Chemistry

$39.99

Reoxidationsschutz von Eisenschwamm

$69.99

Russias Relations with the GCC and Iran

$179.99

Critical Voices in Teacher Education

$109.99

Die Expansion mittelstndischer Handelsbetriebe durch Grozusammenschlsse

$59.99

Schooling for Sustainable Development:

$109.99

Speiserhre Magen Darm

$49.99

Untersuchungen ber den Harnstoff-Stoffwechsel im Myokard, den Lungen und den Kiemen Gewinnung reine

$59.99

In Due Time: Wrong Place, (Really) Wrong Time

$4.46

Lernprozesse Erwachsener in migrationsbedingten bergngen

$79.99

Risks and Security of Internet and Systems

$59.99

The Frontiers of Applied Demography

$99.00

Handbuch Web Mining im Marketing

$64.99

Cardiac Regeneration

$199.99

Jahrbuch der Psychoonkologie 1996

$59.99

Combinatorial Peptide Library Protocols

$84.99

Two Tough Trucks: Two Tough Trucks Get Lost

$4.49

Emerging Infections in Asia

$54.99

Dynamical Systems on Networks

$49.99

The Defence of Western Europe

$39.99

Analysis of Neural Data

$149.00

Steuerfall und Lsung

$59.99