Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Mitochondria and the Heart

Mitochondria and the Heart

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9780387255743
Condition
New
Product Description

Mitochondria have been pivotal in the development of some of the most important ideas in modern biology. Since the discovery that the organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an extraordi-nary number of publications have followed, and the term mitochondrial medicine was coined. Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases. Besides its role in adenosine triphosphate generation, mitochondria regu-late a complex network of cellular interactions, involving (1) generation and detoxification of reactive oxygen species, including superoxide anion, hy-drogen peroxide, and hydroxyl radical; (2) maintenance of the antioxidant glutathione in a reduced state and adequate level of mitochondrial matrix superoxide dismutase; (3) cytoplasmic calcium homeostasis, particularly under conditions of cellular calcium loading; (4) transport of metabolites between cytoplasm and matrix; (5) both programmed (apoptosis) and necrotic cell death; and (6) cell growth and development. It is therefore not surprising that this organelle has come to be the center stage in many current investigations of cardiovascular diseases, aging, and agi- related disease. Concomitant with these advances, an impressive effort is under- way for the development of new tools and methodologies to study mitochondrial structure and function, including powerful ways to visualize, monitor, and alter the organelle function to assess the genetic consequences of these perturbations.

Available Colors
Available Sizes
1 Offer Price Range: $169.00 - $169.00
BEST PRICE

Single Product Purchase

$169.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$169.00 $169.00

$169.00
See Site In stock Visit Store

Similar Products

Proceedings of International Conference on Communication and Computational Technologies

$219.99

Prenatal Family Dynamics

$159.99

Testis, Epididymis and Technologies in the Year 2000

$169.99

Information Hiding

$54.99

Advances in Time Series Methods and Applications

$109.00

User Innovation in Healthcare

$64.99

Dorf

$99.00

Communication, Devices, and Computing

$219.99

Evolutionary Biology

$39.99

Iron Oxide-Based Nanocomposites and Nanoenzymes

$139.00

Ingenieurakustik

$44.99

Control of Partially-Known Dynamical Systems

$39.99

Literature of Mysticism in Western Tradition

$84.99

Japanese Global Strategy

$179.99

Phytolith Systematics

$199.99

Advanced Data Mining and Applications

$99.99

Design of Structural Elements with Tropical Hardwoods

$109.99

Organic Inhibitors of Corrosion of Metals

$169.99

Human Brain Stem Vessels

$549.00

Versuche zum Verformungsvermgen von Stahlbetontrgern

$49.99

Long Non-coding RNAs in Human Disease

$109.99

Big Data Analytics and Computational Intelligence for Cybersecurity

$169.99

Empirische Polizeiforschung

$59.99

Poems and Contexts: Yeats Annual No.16

$109.99

Coxeter Graphs and Towers of Algebras

$99.00

Tiny T. Rex: Tiny T. Rex and the Grand Ta-Da

$5.21

The Design of Low Noise Oscillators

$129.00

Grndervter

$44.99

Sozialer Wandel

$39.99

Guide to Observing Deep-Sky Objects

$29.95

Shape Detection in Computer Vision Using the Hough Transform

$54.99

IRONBinary Phase Diagrams

$54.99

Computer Performance Engineering

$54.99

Family Life in Old Age

$109.99

Das Urbild des Elementaren Atoms

$44.99

Digitalization Cases Vol. 2

$79.99

Heiner Mller-Handbuch

$99.99

One Crazy Summer

$7.46

The Physics of Invisibility

$32.99

The Role of Regional Organizations in the Context of Climate Change

$129.00