Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Molecular Structures and Structural Dynamics of Prion Proteins and Prions

Molecular Structures and Structural Dynamics of Prion Proteins and Prions

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9789401773188
Condition
New
Product Description

This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by the body's own proteins, are invariably fatal and highly infectious neurodegenerative diseases effecting humans and almost all animals for a major public health concern. Prion contains no nucleic acids and it is a misshapen or conformation-changed protein that acts like an infectious agent; thus prion diseases are called protein structural conformational diseases. PrPC is predominant in -helices but PrPSc are rich in -sheets in the form as amyloid fibrils; so very amenable to be studied by MD techniques. Through MD, studies on the proteinstructures and the structural conversion are very important for revealing secrets of prion diseases and for structure-based drug design or discovery. Rabbits, dogs, horses and buffaloes are reported to be the few low susceptibility species to prion diseases; this book's MD studies on these species are clearly helpful to understand the mechanism underlying the resistance to prion diseases. PrP(1-120) usually has no clear molecular structures; this book also studies this unstructured region through MD and especially MM techniques from the global optimization point of view. This book is ideal for practitioners in computing of biophysics, biochemistry, biomedicine, bioinformatics, cheminformatics, materials science and engineering, applied mathematics and theoretical physics, information technology, operations research, biostatistics, etc. As an accessible introduction to these fields, this book is also ideal as a teaching material for students.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$129.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

$129.00
See Site In stock Visit Store

Similar Products

Brazilian Psychosocial Histories of Psychoanalysis

$159.99

Gedchtnistraining 50+ planen, durchfhren und evaluieren

$17.99

The Visionary Package

$54.99

I Can Read! Level 1 - Amelia Bedelia: Amelia Bedelia Gets a Break

$4.46

Aufsichtsratsarbeit in kommunalen Unternehmen

$69.99

Numerical Probability

$64.99

Unfall und Verbrechen

$44.99

Producing Health Policy

$89.99

Computer-Aided Mechanical Assembly Planning

$169.99

ber die Struktur der positiven Gleitentladung

$59.99

The Structure of Molecules and Ions

$54.99

Integration hochqualifizierter Migranten durch Organisationen

$69.99

Digitale Fernseh- und Hrfunktechnik in Theorie und Praxis

$179.99

Common Cases in Women's Primary Care Clinics

$109.00

Analysis of Images, Social Networks and Texts

$54.99

Legendary Lionesses

$24.99

Aristotelische Diskurse

$49.99

Working with Transgender Young People and their Families

$29.99

Cellular Automata and Groups

$89.00

High-Rate, High-Dimensional Quantum Key Distribution Systems

$109.99

A Color of His Own by Leo Lionni

$8.99

Multilateral Development Cooperation in a Changing Global Order

$54.99

Patient Krankenhaus

$49.99

Hurricane Monitoring With Spaceborne Synthetic Aperture Radar

$169.99

Umkehrung der Steuerschuldnerschaft

$17.99

Worlds Out of Nothing

$29.99

Neural Nets WIRN Vietri-01

$39.99

Ketzer, Kreuzzge, Inquisition

$64.99

Bloomsbury Aesthetics and the Novels of Forster and Woolf

$129.00

Just For You! Level 1: I Hate to Be Sick!

$2.99

Informatik fr Maschinenbauer

$59.99

Plants vs. Zombies: The Garden Path

$5.99

Modern Biochemical Engineering

$39.99

Die Dynamik von Konsumgtermrkten

$59.99

Artificial Neural Networks for Intelligent Manufacturing

$129.00

International Economic Interdependence, Patterns of Trade Balances and Economic Policy Coordination

$109.99

Stochastic Theory and Adaptive Control

$39.99

White Coat Tales

$54.99

Analyse der Fette und Wachsarten

$44.99

New Journalism Ecologies in East and Southern Africa

$119.00