Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Cell Line Development

Cell Line Development

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9789048122455
Condition
New
Product Description

Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms. This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity, improve cell function, glycosylation and secretion and control apoptosis. It presents an overall picture of the current topics central to expression engineering including such topics as epigenetics and the use of technologies to overcome positional dependent inactivation, the use of promoter and enhancer sequences for expression of various transgenes, site directed engineering of defined chromosomal sites, and examination of the role of eukaryotic nucleus as the controller of expression of genes that are introduced for production of a desired product. It includes a review of selection methods for high producers and an application developed by a major biopharmaceutical industry to expedite the cell line development process. The potential of cell engineering approch to enhance cell lines through the manipulation of single genes that play important roles in key metabolic and regulatory pathways is also explored throughout.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$129.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

$129.00
See Site In stock Visit Store

Similar Products

Investitionsgtereinkauf

$39.99

Studies in Mathematical Physics

$169.99

Epic! Animal Rescue Friends: Animal Rescue Friends

$7.49

Die pileaten Porlinge Mitteleuropas

$49.99

Microfluidic and Compartmentalized Platforms for Neurobiological Research

$109.99

Scenes and Communities in the City

$59.99

The Ontology of Gods

$44.99

Deskriptive Statistik

$44.99

Laborpraxis Band 3: Trennungsmethoden

$39.99

Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease

$84.99

Advanced Magnetic Resonance Techniques in Systems of High Molecular Complexity

$54.99

Armut von Familien im sozialen Wandel

$64.99

Decision-Making in an Organizational Context

$54.99

Convergence or Divergence in Europe?

$109.99

Weird Weather

$44.99

Modeling, Identification and Control Methods in Renewable Energy Systems

$159.99

Leading by Coaching

$44.99

Manual of Plastics Analysis

$219.99

The Role of Student Services in Higher Education

$159.99

Exploring the Social and Political Economy of Alexis de Tocqueville

$159.99

Fundamentals of Incompressible Fluid Flow

$109.99

Social Development

$20.80

Wege zum Reichtum

$74.99

Mine Planning and Equipment Selection

$429.00

Little Scholastic: The Tiny Tadpole

$5.24

New Eyes on the Sun

$29.99

Samsung ARTIK Reference

$44.99

Transforming Enterprise Cloud Services

$169.99

Ordinary and Partial Differential Equations

$44.99

The Birth of Science

$37.99

Nudge im Spiegel des allgemeinen Persnlichkeitsrechts

$84.99

Wolves and Dogs

$119.99

Krankheiten des Nervensystems

$84.99

Knee Arthroplasty

$149.00

Can You See What I See?: Hidden Wonders (Hardcover)

$11.24

Irish Literature in Italy in the Era of the World Wars

$119.99

Pro Microsoft Power BI Administration

$54.99

Integrated Spatial and Energy Planning

$59.99

Aktionrsorientierte Unternehmensfhrung

$69.99

Chuang-Tzu

$54.99