Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Cell Line Development

Cell Line Development

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9789048122455
Condition
New
Product Description

Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms. This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity, improve cell function, glycosylation and secretion and control apoptosis. It presents an overall picture of the current topics central to expression engineering including such topics as epigenetics and the use of technologies to overcome positional dependent inactivation, the use of promoter and enhancer sequences for expression of various transgenes, site directed engineering of defined chromosomal sites, and examination of the role of eukaryotic nucleus as the controller of expression of genes that are introduced for production of a desired product. It includes a review of selection methods for high producers and an application developed by a major biopharmaceutical industry to expedite the cell line development process. The potential of cell engineering approch to enhance cell lines through the manipulation of single genes that play important roles in key metabolic and regulatory pathways is also explored throughout.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$129.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

$129.00
See Site In stock Visit Store

Similar Products

Techniques in Pheromone Research

$99.00

Tolkien

$54.99

Improved Understanding of Past Climatic Variability from Early Daily European Instrumental Sources

$169.99

Qualitt von Softwaresystemen

$74.99

Siebenstellige Tafeln der elementaren transzendenten Funktionen

$34.99

The Underdogs

$5.24

The Burning Maze (The Trials of Apollo Series #3) by Rick Riordan

$9.99

How Do Dinosaurs Stay Safe? (Hardcover)

$14.24

Schizophrenia

$39.99

Paradoxes in Probability Theory

$69.99

From QCD Flux Tubes to Gravitational S-matrix and Back

$109.99

Menschenrechte und europische Auenpolitik

$64.99

Building Trust in Information

$84.99

Thromboembolie-Prophylaxe in der Inneren und operativen Medizin

$69.99

"Dann ist Vergangenheit bestndig"

$39.99

Basiswissen Bilanzanalyse in der Hotellerie

$19.99

Quantum Measurements in Optics

$39.99

Verringerung gesundheitlicher Ungleichheit durch Empowerment

$49.99

Ideology and Cinematography in Hollywood, 1930-1939

$169.99

Dialog Systems

$129.99

Exogene Osteomyelitis von Becken und unteren Gliedmaen

$54.99

Obstruction Theory

$44.99

Databases Theory and Applications

$54.99

Neuroimaging of Schizophrenia and Other Primary Psychotic Disorders

$99.00

EBM 2015 - Kommentierter Einheitlicher Bewertungsmastab

$69.99

Demokratietheorie in Lateinamerika

$59.99

Particles and Inorganic Clusters

$109.99

Fermions and Anomalies in Quantum Field Theories

$99.00

Technological Advancement in Algal Biofuels Production

$249.99

Politische Sozialisation Jugendlicher in der Nachwendezeit

$59.99

Amines and Their Metabolites

$129.00

The Graph Theoretical Approach in Brain Functional Networks

$19.99

Vasopressin

$39.99

Status Epilepticus

$84.99

Grundlagen und neue Perspektiven des Luxustourismus

$49.99

Sustainable Strategies for the Upgrading of Natural Gas: Fundamentals, Challenges, and Opportunities

$329.99

Digital Grid

$89.00

Effects of Exercise on Hypertension

$109.99

Sensors & Instrumentation and Aircraft/Aerospace Testing Techniques, Volume 8

$249.99

Robot Behaviour

$39.99