Biologie und Epidemiologie der Hormonersatztherapie - Biology and Epidemiology of Hormone Replacemen

Name: Biologie und Epidemiologie der Hormonersatztherapie - Biology and Epidemiology of Hormone Replacemen
Brand: Springer Nature
SKU: 9783540378617
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Springer Nature

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9783540378617

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Die Vor- und Nachteile der Hormonersatztherapie (HRT) werden von einer Expertengruppe hinsichtlich der epidemiologischen Beweislage diskutiert. Obwohl alle positiven und negativen Aspekte der HRT behandelt werden, liegt der Schwerpunkt der Diskussionen bei der Frage des Brustkrebsrisikos. Unter anderem wird gezeigt, dass die aus epidemiologischen Studien abgeleiteten Ergebnisse sich nicht mit den Wachstumseigenschaften dieser Tumoren decken so dass weiterfhrende Bevlkerungsuntersuchungen unter Einbeziehungen pathobiologischen Sachverstands notwendig erscheinen. This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of the current evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT, including issues concerning psychology, the cardiovascular system, bone structure, and carcinogenesis. It focuses, however, on cancer risk and on risk of breast cancer in particular. In doing so, it provides a detailed discussion of the pathobiological features of breast cancer, concluding that the evidence provided by epidemiological studies is in conflict with the biological growth features of breast cancer. It advocates further epidemiological studies which incorporate pathobiological assessments.

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