Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

G Protein-Coupled Receptors in Drug Discovery

G Protein-Coupled Receptors in Drug Discovery

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781603273169
Condition
New
Product Description

The G protein-coupled receptors (GPCRs) and associated peripheral G proteins underpin a multitude of physiological processes. The GPCRs represent one of the largest superfamilies in the human genome and are a significant target for bioactive and drug discovery programs. It is estimated that greater than 50% of all drugs, including those in development, currently target GPCRs. Many of the characterized GPCRs have known ligands; however, approximately 20% of GPCRs are described as orphan GPCRs, apparent GPCRs that share the generic high-level structure charact- istic of GPCRs but whose endogenous ligand is not known. Therefore, it is expected that the field of GPCR drug discovery and development will greatly expand in the coming years with emphasis on new generations of drugs against GPCRs with unique therapeuticuseswhichmayincludedrugssuchasallostericregulators,inverseagonists, and identification of orphan GPCR ligands. AswelearnmoreaboutthemolecularsignalingcascadesfollowingGPCRactivation, we acquire a better appreciation of the complexity of cell signaling and as a result, also acquire a vast array ofnew molecularmethods toinvestigate these andother processes. Thegeneralaimofthisbookistoprovideresearcherswitharangeofprotocolsthatmay be useful in their GPCR drug discovery programs. It is also the basis for the devel- ment of future assays in this field. Therefore, the range of topics covered and the appropriate methodological approaches in GPCR drug discovery are reflected in this book. Itisinterestingtonotethatfuturedirectionsindrugdiscoverywillrequireinput and collaboration from a plethora of fields of research. As such, this book will likely be of interest to scientists involved in such fields as molecular biology, pharmacology, biochemistry, cellular signaling, andbio-nanotechnology.

Available Colors
Available Sizes
1 Offer Price Range: $84.99 - $84.99
BEST PRICE

Single Product Purchase

$84.99
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$84.99 $84.99

$84.99
See Site In stock Visit Store

Similar Products

The Structure, Dynamics and Equilibrium Properties of Colloidal Systems

$329.99

Endoscopic Skull Base Surgery

$89.00

Intelligent Computing in Smart Grid and Electrical Vehicles

$54.99

International Perspectives on Teaching the Four Skills in ELT

$169.99

Zapato Power: Freddie Ramos Hears It All

$4.46

Error Reduction and Prevention in Surgical Pathology

$79.99

Information Systems Security and Privacy

$54.99

The Secular Decline of the South African Manufacturing Sector

$109.99

Professional Identities in Initial Teacher Education

$109.99

Complex Analysis in One Variable

$99.99

Antike Metallurgie und Mnzprgung

$34.99

Religion, Art, and Visual Culture

$109.99

Advanced Technologies, Systems, and Applications VII

$169.99

Machine Learning, Image Processing, Network Security and Data Sciences

$54.99

Glial Neuronal Signaling

$129.00

Acetylenverluste an Naentwicklern

$54.99

Digital verbunden sozial getrennt

$49.99

Antibiotic Resistance in the Environment

$449.99

Crossroads: Performance Studies and Irish Culture

$54.99

Water Security Across the Gender Divide

$99.00

Poststructural and Narrative Thinking in Family Therapy

$39.99

Fractals in Biology and Medicine

$84.99

Algorithm Theory - SWAT 2004

$54.99

Professionelle Interaktion und Kommunikation

$59.99

Semantics-Directed Compiler Generation

$29.99

Assessment in Music Education: from Policy to Practice

$139.99

Critical Survey of Studies on the Anthropology of Nias, Mentawei and Enggano

$54.99

Radiation: An Energy Carrier

$99.99

Copingmechanismen von Handwerkerinnen in konfliktren Situationen

$49.99

The Calcium Channel: Structure, Function and Implications

$54.99

Machine Learning for Cyber Physical Systems

$129.00

Implementing Systems for Supporting Management Decisions

$219.99

Textbook of Penile Cancer

$99.00

Late Cenozoic Yushe Basin, Shanxi Province, China: Geology and Fossil Mammals

$129.00

Lyrik als Sprache unserer Zeit? Paul Celans Gedichtbnde

$44.99

Smart Objects and Technologies for Social Good

$49.99

PEGIDA

$19.99

What Robots Can and Cant Be

$219.99

Komsomol Participation In The Soviet First Five-Year Plan

$19.99

The Triple Crisis of Western Capitalism

$84.99