Copied Immunogenicity of Biopharmaceuticals
Immunogenicity of Biopharmaceuticals
A particular issue for biopharmaceuticals that has not been addressed comprehensively in any book, is the potential of an immune response to the biopharmaceutical product. That is, the human body marks the drug as a foreign body, and develops antibodies against the drug. These antibodies may be relatively harmless, but may also cross-react with the endogenous compound, causing autoimmunogenicity. Recent adverse experiences in Europe with Janssen-Orthos blockbuster product Eprex has increased the attention towards potential immunogenicity of biopharmaceuticals, above all from the regulatory agencies. This book is intended to give a broad overview of the current state-of-the-art regarding the immune response to biopharmaceuticals. The chapters range from an overview of the immune system and factors that may trigger the immune system, via detection of antibodies and clinical implications, to various case examples and the regulatory view on immunogenicity.
Price Comparison
| Seller | Contact Seller | List Price | On Sale | Shipping | Best Promo | Final Price | Volume Discount | Financing | Availability | Seller's Page |
|---|---|---|---|---|---|---|---|---|---|---|
|
BEST PRICE 1 Product Purchase
|
|
$129.00 | $129.00 |
|
$129.00 | See Site | In stock | Visit Store |
Reviews
Questions & Answers
Violence in Intimate Spaces
$139.99
Evaluation and Management of Blepharoptosis
$84.99
Economy and Culture in Pakistan
$59.99
Zufall und Chaos
$49.99
High-Performance Energy-Efficient Microprocessor Design
$89.00
Geoethics
$29.99
The Language of Female Leadership
$54.99
Structure-Property Relationships under Extreme Dynamic Environments
$39.99
Plant Responses to Drought Stress
$219.99
Authentication in Insecure Environments
$54.99
Deep Learning for Autonomous Vehicle Control
$29.99
Global collaboration, local production
$59.99
Historical Earthquake-Resistant Timber Framing in the Mediterranean Area
$129.00
The Baby-Sitters Club: Kristy and the Walking Disaster
$9.74
Advances in Fashion and Design Research
$169.00
An Anthropological Study of Hospitality
$59.99
Das Gesollte Wollen
$59.99
Learning Transformational Leadership
$169.99
Critical Autoethnography and criture Feminine
$129.99
Sexualstrafrecht in Medizin und Pflege
$17.99
Cardiovascular Pediatric Critical Illness and Injury
$39.99
Mikropolitik politischer Organisationen
$49.99
Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease
$149.00
Nonlinear Water Waves
$69.99
Ethical Issues in Poverty Alleviation
$99.99
Entwicklung und Untersuchung neuartiger Indikatorelektroden zur Titration hochverdnnter Lsungen
$59.99
Traumdeutung
$39.99
Favorite Books Grade 4
$129.00
Das internationale Kooperationsrecht der Europischen Union
$119.99
Nature Inspired Cooperative Strategies for Optimization (NICSO 2010)
$169.99
Multisensory Landscapes
$89.00
Wireless Localization Techniques
$169.99
Gendered Migrations
$89.00
The Human Blood Basophil
$84.99
Drugs of Abuse, Immunomodulation, and Aids
$39.99
Medical Imaging and Augmented Reality
$54.99
The Early Computer Industry
$109.99
Hydrogeologische Methoden
$139.00
Young Children's Play and Environmental Education in Early Childhood Education
$49.99
Colors and Their Character
$54.99
