Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Gene Quantification

Gene Quantification

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781461241645
Condition
New
Product Description

Geneticists and molecular biologists have been interested in quantifying genes and their products for many years and for various reasons (Bishop, 1974). Early molecular methods were based on molecular hybridization, and were devised shortly after Marmur and Doty (1961) first showed that denaturation of the double helix could be reversed - that the process of molecular reassociation was exquisitely sequence dependent. Gillespie and Spiegelman (1965) developed a way of using the method to titrate the number of copies of a probe within a target sequence in which the target sequence was fixed to a membrane support prior to hybridization with the probe - typically a RNA. Thus, this was a precursor to many of the methods still in use, and indeed under development, today. Early examples of the application of these methods included the measurement of the copy numbers in gene families such as the ribosomal genes and the immunoglo bulin family. Amplification of genes in tumors and in response to drug treatment was discovered by this method. In the same period, methods were invented for estimating gene num bers based on the kinetics of the reassociation process - the so-called Cot analysis. This method, which exploits the dependence of the rate of reassociation on the concentration of the two strands, revealed the presence of repeated sequences in the DNA of higher eukaryotes (Britten and Kohne, 1968). An adaptation to RNA, Rot analysis (Melli and Bishop, 1969), was used to measure the abundance of RNAs in a mixed population.

Available Colors
Available Sizes
1 Offer Price Range: $169.00 - $169.00
BEST PRICE

Single Product Purchase

$169.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$169.00 $169.00

$169.00
See Site In stock Visit Store

Similar Products

Scenario Thinking

$54.99

Biotechnology Proteins to PCR

$109.99

Pi und Co

$29.99

Optimale Entscheidungen in Organisationen

$64.99

Slender PCI

$139.99

Advances and Technical Standards in Neurosurgery

$139.99

Wheat Marketing in Transition

$109.99

Finite Elemente fr Ingenieure 1

$44.99

Geometry of Knowledge for Intelligent Systems

$84.99

Diagnostic and Therapeutic Procedures in Gastroenterology

$219.99

An Accelerated Solution Method for Two-Stage Stochastic Models in Disaster Management

$54.99

Berlin-Report

$44.99

Dictionnaire conomique / Wirtschaftswrterbuch

$59.99

System Reduction for Nanoscale IC Design

$39.99

Animal Horror Cinema

$54.99

Mechanisms of Inorganic and Organometallic Reactions Volume 7

$39.99

Symbolic Analysis of Analog Circuits: Techniques and Applications

$84.99

Expeditionary Surgery at Sea

$129.99

New Perspectives on Mind-Wandering

$109.99

The Archaeologist's Laboratory

$79.99

Distributed Embedded Controller Development with Petri Nets

$54.99

Advances in Computational Plasticity

$84.99

Von hybriden Schlerinnen und Schlern in Dritten Rumen

$64.99

Relativity Physics

$54.99

Principles of Engineering Mechanics

$109.99

Predictive Statistical Mechanics

$109.99

Transnational Performance, Identity and Mobility in Asia

$59.99

Resilience in Papal Rome, 1656-1870

$139.99

Input-to-State Stability

$179.99

Post-Digital, Post-Internet Art and Education

$59.99

Markt und Staat

$44.99

Architecture of Computing Systems ARCS 2015

$54.99

Internationale Krisen-Public Relations

$59.99

Multidimensional and Strategic Outlook in Digital Business Transformation

$179.99

Risiken und Chancen integriert managen

$17.99

Moving Texts, Migrating People and Minority Languages

$99.99

Mi Msica

$3.71

Big Data Analytics

$54.99

Systems, Models and Feedback: Theory and Applications

$39.99

Hands-on Azure Cognitive Services

$79.99