Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Acyclic, Carbocyclic and L-Nucleosides

Acyclic, Carbocyclic and L-Nucleosides

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9780751404340
Condition
New
Product Description

Interest in chemical entities capable of blocking or modifying cell metabolism ultimately goes back to the discovery of the structure of DNA in the 1950s. Understanding of the biochemical processes involved in cell metabolism rapidly led to the idea that compounds could be designed which might interfere with these processes, and thus could be used in the treatment of the diseases caused by viral infection. Since then, several classes of drugs have been discovered which depend for their effect on modification of the proper functioning of nucleic acids and, with the introduction of acyclovir for the treatment of Herpes infections, nucleoside analogues have become the cornerstone of antiviral chemotherapy. The success of the early nucleoside agents, the toxicity and metabolic instability of many nucleoside analogues, and the effects of viral pathogens on public health are driving the design, synthesis and evaluation of new nucleoside analogues, with much attention turning to nucleosides containing `non natural' sugar analogues. This book focuses on the development of these agents, and draws together all the available material in an easily consulted form, which at the same time guides the reader into the research literature on the subject. Written primarily for the medicinal chemist, coverage includes both synthetic strategies and outline guidance on the main trends in biological activity. Particular attention is drawn to the comparison of synthetic routes to compounds with their natural analogues. Finally, the important antiviral activities of the compounds are treated, including anti-retrovirus, anti-hepadnavirus and anti-herpes virus properties. Written mainly for medicinal chemists in the pharmaceutical industry and synthetic organic chemists in academe, this book will also be attractive to researchers in institutions focusing on cellular metabolism. Advanced students of organic chemistry will find the clear discussion of the synthetic strategies adopted in the development of these compounds a useful introduction to this exciting and challenging area.

Available Colors
Available Sizes
1 Offer Price Range: $169.00 - $169.00
BEST PRICE

Single Product Purchase

$169.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$169.00 $169.00

$169.00
See Site In stock Visit Store

Similar Products

Recent Trends in Engineering Design

$169.00

Transformational Sales

$64.99

Performing Women

$19.99

Management of Soft Tissue Sarcoma

$199.99

Protein Reviews

$169.99

The Periodic Table I

$379.99

Art, Equality and Learning: Pedagogies Against the State

$49.99

In the Pursuit of Winning

$109.99

The Quinoa Genome

$169.99

European Trend Atlas of Extreme Temperature and Precipitation Records

$109.99

Cross Regional Trade Agreements

$109.99

Metzler Lexikon Autoren

$59.99

The Maiden Voyage of Petrus van Stijn

$24.99

Hardware-Software Co-Design of Embedded Systems

$169.99

Energy Law and Economics

$179.99

Immortality or Extinction?

$129.00

Revisiting Marxs Critique of Liberalism

$99.99

Gene Mapping in Laboratory Mammals Part B

$54.99

Birth Defects in India

$89.00

Declaration of Peace for Indigenous Australians and Nature

$119.00

Orthomodular Lattices

$84.99

Leitfaden des Hufbeschlages

$84.99

Reimagining Innovation in Humanitarian Medicine

$54.99

Das Weltsystem des Erdls

$39.99

Robotersysteme 2

$39.99

The Worst Fairy Godmother Ever! (Hardcover)

$11.24

Mobile Health Technologies

$99.00

Familien-Atlas II: Lebenslagen und Regionen in Deutschland

$54.99

Scholastic Text Sets Grade 4: Technology & Discovery

$99.00

Lieber Herr Fuchs, lieber Herr Schmatz!

$69.95

Transitioning Media in a Post COVID World

$179.99

Cabinets in Western Europe

$54.99

The Palgrave Handbook of History and Social Studies Education

$249.99

Evolution of Massive Stars

$84.99

Datenbankanwendungen mit FileMaker Pro Version 2

$29.99

Pathophysiology of Headaches

$109.99

Connectomics in NeuroImaging

$54.99

Die Algen

$44.99

Public Art and Urban Memorials in Berlin

$139.99

Subarachnoidalblutungen aus Hirnaneurysmen als Todesursache

$59.99