Copied Targeting Functional Centers of the Ribosome
Targeting Functional Centers of the Ribosome
This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.
Price Comparison
| Seller | Contact Seller | List Price | On Sale | Shipping | Best Promo | Final Price | Volume Discount | Financing | Availability | Seller's Page |
|---|---|---|---|---|---|---|---|---|---|---|
|
BEST PRICE 1 Product Purchase
|
|
$39.99 | $39.99 |
|
$39.99 | See Site | In stock | Visit Store |
Reviews
Questions & Answers
Flexible Arbeitszeitgestaltung im ffentlichen Dienst
$69.99
Optical Coherence Tomography in Age-Related Macular Degeneration
$109.00
William James on Religion
$39.99
Anesthesiology and the Cardiovascular Patient
$169.00
Challenges to Democratic Governance in Developing Countries
$109.99
Ergodic Optimization in the Expanding Case
$39.99
Marlowe's Republican Authorship
$54.99
Complications of Percutaneous Coronary Intervention
$179.99
Shakespeare, Bakhtin, and Film
$109.99
US National Security Concerns in Latin America and the Caribbean
$54.99
Digital Terrain Modelling
$129.00
International Perspectives on Cyberbullying
$99.99
Reflux Aspiration and Lung Disease
$129.99
Science, Medicine and Cultural Imperialism
$39.99
The Government of the Peoples
$39.99
Technologies for Interactive Digital Storytelling and Entertainment
$54.99
Introduction to Video Game Engine Development
$59.99
Bond Portfolio Optimization
$79.99
Type Synthesis of Parallel Mechanisms
$129.00
Description Logics in Multimedia Reasoning
$89.00
The Blood-Retinal Barriers
$84.99
Applied Scanning Probe Methods XIII
$89.00
Brazing
$219.99
Unbedingte Wahrheit und endliche Vernunft
$49.99
Resistance, Liberation Technology and Human Rights in the Digital Age
$109.99
Discovery Science
$39.99
Cellular Genetic Algorithms
$39.99
The Adventures of Captain Underpants (Hardcover)
$7.50
Bericht ber die Achtundvierzigste Zusammenkunft der Deutschen Ophthalmologischen Gesellschaft in He
$59.99
Die Entwicklung des Systems Erde
$49.99
Traumatic Brain Injury Rehabilitation
$54.99
Supercomputer 92
$69.99
F Fluorine
$99.00
New Method of Identifying Family Related Skulls
$84.99
Emerging Technologies in Data Mining and Information Security
$169.00
Chemokines and Viral Infection
$169.99
Rntgenfluoreszenz-Untersuchungen an kleinen Feststoff-Oberflchen und konzentrierten Salzlsungen
$59.99
Imaging of the Knee
$219.99
Semantics, Applications, and Implementation of Program Generation
$39.99
Eco-friendly Agro-biological Techniques for Enhancing Crop Productivity
$169.99
