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Bioinformatik

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Brand
Springer Nature
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N/A
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GTIN
9783764362539
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Product Description

Locker und leicht verstndlich geschrieben fhrt dieser Leitfaden in die Grundlagen und Mglichkeiten der Sequenzanalyse ein. Das Buch beginnt mit einer Einfhrung in die wichtigen Sequenzdatendatenbanken am NCBI und EMBL sowie in die wachsende Zahl der Motivdatenbanken. Anschlieend werden die einfachsten Methoden des paarweisen Sequenzvergleiches in globalen und lokalen Alignments beschrieben sowie die gngigsten heuristischen Verfahren der Datenbanksuche (FASTA und BLAST). Multiple Alignments, Substitutionsmatrizen und die Berechnung phylogenetischer Bume werden dem Leser nahe gebracht. Neu hinzugekommen sind auch Erluterungen der Prinzipien der Genomanalyse und der gngigsten Algorithmen zur Genvorhersage. Zu jeder Methode werden Online-Tools im Internet oder freie Software angegeben. Das Buch richtet sich an Anwender und Einsteiger in die Bioinformatik, speziell Studenten und Forscher, die sich mit der Sequenzanalyse auseinandersetzen mssen.

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