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Reitende Gefe des Herzens

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Springer Nature
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9783540076414
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Soll zu Fragen der formalen Teratogenese des Herzens und der groen arteriellen Blutgefe Stellung genommen werden, ist die Kenntnis der nor malen Herzentwicklung eine unabdingbare Voraussetzung (Goerttler, 1963 b). Erste grundlegende Erkenntnisse und Beschreibungen wesentlicher embryonaler Herz strukturen vermitteln hier die ausfhrlichen Arbeiten von W. His (1880,1882, 1885) und Born (1889) sowie die Monographie der gesamten Herzentwicklung von Tandler (1913). In der formalen Teratologie des Herzens darf die Schrift C. von Rokitanskys (1875) "Die Defekte der Scheidewnde des Herzens" aus dem Jahre 1875 - vor ziemlich genau 100 Jahren entstanden - als frher Hhepunkt gelten. Seine schematische Einteilung der Kammerseptumdefekte ist, wenn auch in modifizierter Form (Goerttler, 1960; Doerr, 1967), bis heute fhrend. Zugleich rckt seine Einteilung der Mibildungen des arteriellen Herzendes - bedingt durch eine abartige bulbotrunkale Septation - das Problem der Transposition und Inversion in den Mittelpunkt der Mibildungslehre des menschlichen Herzens. Seine Theorie wird spter von Mnckeberg (1924) aufgegriffen und neu formuliert (Kritik durch Bredt, 1935, 1936). Auerdem bedeutet sie einen ent scheidenden Impuls fr die Arbeiten Spitzers (1919, 1921, 1923, 1929), die durch eine phylogenetische Deutung der Entwicklung des Herzens und der Mibildungen sowie durch die Anerkennung der Bedeutung hmodynamischer Faktoren fr die nicht auto chthone Ausbildung der Septation von grundlegender Bedeutung sind.

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