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Zerebrale Effekte der hypothermen extrakorporalen Zirkulation

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Springer Nature
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N/A
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9783540529712
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Product Description

Angaben ber die Inzidenz neurologischer und psychischer Funktionsstrungen nach kardiopulmonalen Bypassoperationen reichen in verschiedenen klinischen Untersuchungen von 5 bis 64 %, wobei die Funktionsausflle von leichten neurologischen Vernderungen bis zu zerebralen Infarkten reichen. Die Hufigkeit objektivierbarer Enzephalopathien wird 3 Monate nach kardiopulmonalem Bypass mit etwa 12 % angegeben. Vor diesem Hintergrund lassen sich aus der durch Hypothermie und kardiopulmonalem Bypass vernderten zerebralen Homostase theoretische berlegungen zur mglichen Ursache neurologischer und neuropsychologischer Strungen ableiten. Mit diesem Buch wird erstmals eine systematische Studie ber das Verhalten von Hirndurchblutung, zerebralem Metabolismus, EEG-Verlufen und postoperativer Inzidenz neurologischer/neuropsychologischer Symptomatik nach pulsatiler und nichtpulsatiler Perfusionstechnik in Verbindung mit Hypothermie vorgelegt. Das Kernergebnis aus dieser Untersuchung zeigt, da ein nicht temperaturkorrigiertes Sure-Basen-Management whrend der extrakorporalen Zirkulation und Hypothermie fr das Gehirn physiologischer ist und die Kopplung zwischen Hirnmetabolismus und Durchblutung unter diesen Bedingungen erhalten bleibt.

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