Copied Covalent Catalysis by Enzymes
Covalent Catalysis by Enzymes
Some years ago one of my students and I reported that the acetate kinase reaction is mediated by a phosphorylated form of the enzyme [R. S. Anthony and L. B. Spector, lBe 245, 6739 (1970)]. The reversible reaction between ATP and acetate to give acetyl phosphate and ADP had hitherto been thought to proceed by direct transfer of a phosphoryl group from A TP to acetate in a single-displacement reaction. But now it became clear that acetate kinase was one of that substantial number of enzymes whose mech anism is that of the double displacement. For some reason, I began to wonder about the possibility that all enzymes, like acetate kinase, are double displacement enzymes, and do their work by covalent catalysis. For one thing, I could not think of a single instance of an enzyme for which single displacement catalysis had been proved, and inquiries on this point among knowledgeable friends elicited the same negative response. Moreover, it was long known that the two other kinds of chemical catalysis~homo geneous and heterogeneous~occur through the intermediary formation of a covalent bond between catalyst and reactant. I began to feel confident that chemical catalysis by enzymes must happen the same way.
Price Comparison
| Seller | Contact Seller | List Price | On Sale | Shipping | Best Promo | Final Price | Volume Discount | Financing | Availability | Seller's Page |
|---|---|---|---|---|---|---|---|---|---|---|
|
BEST PRICE 1 Product Purchase
|
|
$39.99 | $39.99 |
|
$39.99 | See Site | In stock | Visit Store |
Reviews
Questions & Answers
Plasmaphysik und Fusionsforschung
$44.99
Arbeit und Freiheit
$17.99
An Introduction to the Greek Theatre
$54.99
Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models
$84.99
Osseous Projectile Weaponry
$79.99
Survival Analysis
$64.99
BBC micro:bit Recipes
$54.99
Sunny Side Up (Hardcover)
$18.74
Cell Migration
$169.99
The Pharmacology of Sleep
$549.99
Microscopy of Semiconducting Materials
$219.99
Issues in Materials Development
$39.99
Beginning Facebook Game Apps Development
$29.99
Crash From Outer Space
$7.49
State, Community and Neighbourhood in Princely North India, c. 1900-1950
$54.99
We Write
$3.71
Frames Framing Framing-Effekte
$44.99
Fhrung von Minderheitsbeteiligungen in Deutschland
$74.99
Machine Learning: ECML'97
$39.99
Unternehmensverkauf
$39.95
Die Kultivierung der Freiheit bei der Macht
$39.99
Die Agenda 2030 als Magisches Vieleck der Nachhaltigkeit
$44.99
Leitfaden der praktischen Dermatologie
$59.99
Modelling Spatial Knowledge on a Linguistic Basis
$39.99
Biophotonics
$39.99
Die Interferenzen von Rntgen- und Elektronenstrahlen
$69.99
Politics, Managerialism, and University Governance
$54.99
Genetic Improvement of Tomato
$84.99
Ubuntu Mandela fr Fhrungskrfte
$17.99
City Branding
$84.99
Detection of Bulk Explosives Advanced Techniques against Terrorism
$219.99
Fragilittsfrakturen des Beckenrings
$17.99
Musiklehramt und Biographie
$44.99
ICT for Intelligent Systems
$279.99
Managerial marketing
$54.99
Cooperation and Competition in a Common Market
$54.99
Beginning Ubuntu Linux
$29.99
Wissenschaftliche Weiterbildung als Transformationsproze
$59.99
Clean Energy Transition-via-Biomass Resource Utilization
$179.99
The Boy Who Failed Show and Tell
$5.99
