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Friedrich Wilhelm Sertrner

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Brand
Springer Nature
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N/A
Part Number
0
GTIN
9783662655627
Condition
New
Product Description

Originaltext mit ausfhrlichem Kommentar von Christoph Friedrich Die zu Beginn des 19. Jahrhunderts aus Arzneipflanzen isolierten Alkaloide waren hochwirksame Stoffe und zugleich Modelle fr die Entwicklung synthetischer Arzneistoffe. Morphin, 1804/05 von Friedrich Wilhelm Sertrner (17831841) als erstes Alkaloid entdeckt, ist ein starkes Schmerzmittel (Analgetikum). Seine Entdeckungsgeschichte kann anhand der hier abgedruckten und erluterten Verffentlichungen Sertrners minutis nachverfolgt werden. Morphin zeigte als Wirkstoff des Opiums (principium somniferum) eine schlafbringende Wirkung) und Sertrner stellte fest, dass es sich bei diesem Stoff um eine Pflanzenbase (Alkaloid) handelt. Heroische Selbstversuche zeigten, dass bereits mit geringsten Mengen eine groe Wirkung erzeugt werden kann. Das Buch schildert Leben und Werk Sertrners. Er gilt als einer der bedeutendsten Apotheker des 18./19. Jahrhunderts, der mit seiner Morphin-Entdeckung ein neues Forschungsgebiet begrndete und den Weg in die moderne Arzneimittelforschung wies.

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