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Analyse des tumorrelevanten Proteins Survivin

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Springer Nature
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N/A
Part Number
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GTIN
9783658085414
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New
Product Description

Cecilia Vallet untersucht, wie der Wechsel zwischen der monomeren und der dimeren Form des Proteins Survivin reguliert ist. Survivin ist in nahezu allen malignen Tumorerkrankungen berexprimiert und durch seine Rolle als Zellzyklus-Regulator und Apoptose-Inhibitor an zwei entscheidenden Prozessen der Onkogenese beteiligt. Es wird angenommen, dass Survivin im Rahmen seiner Funktionen als Zellzyklus-Regulator und Apoptose-Inhibitor als Monomer agiert, wohingegen es in Lsung als Homodimer vorliegt.

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