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Ruthenium-NHC-katalysierte asymmetrische Arenhydrierung

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Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9783658089665
Condition
New
Product Description

Christoph Schlepphorst entwickelt ein rationales Ligandendesign fr die Ruthenium-NHC-katalysierte asymmetrische Hydrierung (hetero-)aromatischer Verbindungen. Zudem synthetisiert er eine Reihe von entsprechenden Carbenvorlufern und charakterisiert diese. Die synthetisierten Carbenvorlufer werden auerdem auf ihre Eignung als Liganden in Ru-NHC-katalysierten Hydrierreaktionen getestet. Der Autor optimiert bei diesem Vorgehen die asymmetrische Hydrierung ungeschtzter monosubstituierter Pyrazine im Hinblick auf die Reaktionsbedingungen und kann Enantiomerenverhltnisse von bis zu 91:9 mit einem der neuen Liganden erreichen.

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