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-Strang-Ausbildung eines Faltungsintermediates von BamA

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Springer Nature
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N/A
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GTIN
9783658290283
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New
Product Description

Sascha Herwig beschreibt die Faltung und den Einbau von -Fass-Membranproteinen am Modell des essenziellen BamA aus Auenmembranen von Escherichia coli, der zentralen Untereinheit des -Barrel-Assembly-Machinery-Komplexes. Membranproteine des -Fass-Typs der Auenmembranen von Bakterien oder Zellorganellen werden ber diesen Komplex eingebaut. Mit ortsgerichteter Fluoreszenzspektroskopie des -Strangs 9 der insgesamt 16 -Strnge umfassenden BamA-Membrandomne wird in Modellmembranen nachgewiesen, dass der Strang in einem Faltungsintermediat bereits in adsorbierter Form parallel zur Membranoberflche entsteht.

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