Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Targeting the Broadly Pathogenic Kynurenine Pathway

Targeting the Broadly Pathogenic Kynurenine Pathway

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9783319118703
Condition
New
Product Description

Tryptophan metabolism via kynurenine pathway plays a critical role in both health and a variety of human diseases. This book highlights the known associations between kynurenine pathway andvarious disease states, as well as examines the current status of drug development and clinical trials of compounds known to alter tryptophan metabolism. The research plays a critical role in molecular targeted therapies directed at altering the kynurenine pathway of tryptophan metabolism.The initial and rate-limiting step of tryptophan metabolism is mediated by one of two enzymes, tryptophan-2,3-dioxygenase (TDO; predominantly in the liver, but also in the brain) and indoleamine-2,3-dioxygenase (IDO; in a host of tissues in response to immune activation). Targeting the enzymes IDO and TDO, as well as other downstream effectors would therefore be likely to generate novel treatment options that would be helpful in a wide variety of clinical settings. This book provides a unique bridge between basic mechanistic understanding of the role of the kynurenine pathway with translational applications and clinical relevance. It will explore the indications that tryptophan metabolism is a potential biomarker of disease activity, can contribute to local and possibly systemic immune suppression in cancer, and is an attractive target for which a variety of inhibitors are readily available.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$116.10
@ Link.springer.com with extra coupon Get Coupon & BUY

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

10% OFF
This deals requires coupon Get Code Here
$116.10
See Site In stock Visit Store

Similar Products

ARIS in der Praxis

$59.99

Try a Little Kindness

$3.74

Daniel Bell und der Kreis der New York Intellectuals

$49.99

Mensch und Kultur

$59.99

The Future of Health, Wellbeing and Physical Education

$39.99

Integrierte Digitale Schaltungen

$149.99

Consumer Credit in the United States

$39.99

Cooperative Stochastic Differential Games

$109.99

MKT+

$59.99

Enhancing Employability in Higher Education through Work Based Learning

$129.99

Project-Based Leisure

$44.99

Environmental Risk Analysis for Asian-Oriented, Risk-Based Watershed Management

$139.99

Innovation in Beratungsunternehmen

$74.99

Computer Network Security

$39.99

Philosophy and Oscar Wilde

$129.99

Linear and Nonlinear Electron Transport in Solids

$54.99

Reading Women's Worlds from Christine de Pizan to Doris Lessing

$54.99

Interdisciplinary Perspectives on Consciousness and the Self

$109.99

Radiotherapy in Prostate Cancer

$109.99

The Plant Diversity of Malesia

$219.99

The World Geopolitics of Drugs, 1998/1999

$109.99

A Primer of Dutch Seventeenth Century Overseas Trade

$54.99

Mergers & Acquisitions in the Machinery Industry

$39.99

Cognitive Systems and Signal Processing

$39.99

Kostenmanagement im Outsourcing von Logistikleistungen

$59.99

Beginning VB 2008

$39.99

Sangspruchdichtung

$19.99

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5

$219.99

Wind Effects on Buildings and Design of Wind-Sensitive Structures

$109.99

Organization Design

$49.99

Indie Video Game Development Work

$119.00

Arthritis Research

$89.00

Introduction to French Classical Tragedy

$44.99

Bowel Radiology

$109.99

Vegetation of the Canary Islands

$199.99

Higher Education, Youth and Migration in Contexts of Disadvantage

$54.99

Fractal Geometry and Stochastics III

$84.99

School Belonging in Adolescents

$69.99

Einstein Anderson Science Geek: The Mighty Ants

$3.71

Broadband Networks, Smart Grids and Climate Change

$84.99