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Molekulare Mechanismen der Zellalterung und ihre Bedeutung fr Alterserkrankungen des Menschen

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Springer Nature
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9783662482490
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Dieses Buch fhrt in die wichtigsten Theorien des Alterns ein; es konzentriert sich auf Telomere, DNA-Schdigung, oxidativen Stress, die Rolle der Nhrstoffversorgung bzw. -erkennung, das Zusammenspiel von Genen und Umwelt (Epigenetik) und die Proteinhomostase und stellt einige Gene vor, die die Lebensdauer in Modellorganismen zu verndern in der Lage sind. Indem es die verschiedenen das Altern bestimmenden Faktoren mit Erkrankungen des Menschen verknpft, sucht das Buch ihre vielfltigen Wechselbeziehungen und Abhngigkeiten aufzuzeigen und zu einer molekularen Matrix des Alterns zusammenzufhren. Von diesem Buch werden alle profitieren, die sich einen profunden berblick ber die Mechanismen der Zellalterung und ihre Verknpfung mit altersassoziierten Erkrankungen des Menschen verschaffen wollen.

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