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Die Biokompatibilitt peritonealer Adhsionsbarrieren

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Springer Nature
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N/A
Part Number
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GTIN
9783658130374
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New
Product Description

Volker H. Schmitt untersucht die Gewebereaktion auf fnf Barrierematerialien histologisch, immunhistochemisch und ultrastrukturell. Der Autor kann zeigen, dass der ultrastrukturelle Befund mit dem makroskopischen Ergebnis korreliert, die effektivste Barriere zeigte das grte Ausma an Remesothelialisierung. Eine bislang als negativ interpretierte Inflammation ging mit geringerer Adhsionsbildung einher. Es gab keine Korrelation zwischen dem Vorhandensein CD68-positiver Makrophagen und der Gewebereaktion. Solche Untersuchungen der Biokompatibilitt und Oberflchenmorphologie sind essentiell fr die Weiterentwicklung materialbasierter Anstze, weg von rein physikalischen Barrieren hin zu funktionalen Biomaterialien im Sinne des Tissue Engineering. Diese Untersuchung ist praxisnah und weiterfhrend, da durch serosale Schdigung entstehende peritoneale Adhsionen eine hufige Komplikation in der Abdominalchirurgie darstellen.

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