To satisfy the food demands of the global population, advanced technology based research is needed, that can extract the information from the plant metabolism and microbial gene pool and use it for improving plant health and productivity. Modern biotechnological tools have the ability to unlock the limitations of agricultural practices. However, the application of these tools is not well equipped. Moreover, eco-friendly agriculture by microbial inoculants is known to have positive influences on soil/plant health. Therefore it is relevant to explore the plant associated microbial niches, especially endophytes, epiphytes, and soil microbes and understand how they are benefitting each other. It can open new insights to develop sustainable agriculture practices by using consortia of microbes as plant helpers that recover the imbalanced agriculture systems and manage pathogenic diseases. This book presents the updates about the plant associated microbiomesand their contemporary uses. It covers the knowledge gap between soil and plant helper microbiomes and their application in the agriculture and allied sectors. Modern insights of phytobiomes are explored in various chapters on a variety of interrelated aspects of the fascinating areas like plant microbial interaction, integrated pest management, soil fertility intensification, sustainable crop production, and disease management. Sections in the book describe how to plant beneficial microbiomes have been utilized for sustainable green farming, with the aim to resolve the global food problem without harming the soil and environment health. This book is intended for everyone who is involved in agriculture, microbial biotechnology, bioinformatics, and all disciplines related to microbial biotechnology. These include academic students, scientists, and researchers at universities, institutes, industries, and government organizations who want to understand microbial linkages in a shorter time. It contains basic information that will be help to the non-specialist readers to understand progressive research.