Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

The Evaluation of New Antiarrhythmic Drugs

The Evaluation of New Antiarrhythmic Drugs

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9789400982727
Condition
New
Product Description

Thus, there are now several chronic canine myocardial infarction ventricular tachyarrhythmia models which are available for the evaluation of new antiarrhythmic drugs (Table I). The available models fulfill many, but not all of the requirements for an ideal chronic arrhythmia model (Table 11). The sustained arrhythmias initiated in these models using programmed pacing presumably have the same localized reentrant mechanism that characterizes chronic human myocardial infarction and chronic coronary 26 artery disease. However, these models are not suitable for determining whether a new drug will abolish spontaneous ly-occurring PVCs. In addition, these models are of unproven value in the study of acute spontaneously occurring sudden death; although recently initiated, provocative work may shed further light on this subject. Most importantly, the available models do seem well-suited to the evaluation of new drugs intended for use in chronic coronary artery disease patients at risk for sustained reentrant ventricular tachycardia or VF. Notably, the results of preliminary electropharmacologic studies in these canine models parallel closely those findings reported in human patients with sustained life-threatening ventricu lar tachyarrhythmias (Table Ill). Therefore, increased use of these chronic models for new antiarrhythmic drug testing is strongly recommended. TABLE II Ideal vs Available Chronic Canine - Arrhythmia Models Ideal Available 1. (a) Arrhythmia mechanism comparable to Yes patients with chronic CAD: Reentry (b) Pathophysiology similar (e. g. , atherogenic CAD) No 2. Susceptible to: (a) spontaneous PVCs No l No (b) spontaneous VT/VF (c) inducible VT/VF Yes 3.

Available Colors
Available Sizes
1 Offer Price Range: $39.99 - $39.99
BEST PRICE

Single Product Purchase

$39.99
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$39.99 $39.99

$39.99
See Site In stock Visit Store

Similar Products

Sequential Learning and Decision-Making in Wireless Resource Management

$109.99

Cellular Fatty Acid-Binding Proteins II

$219.99

Encyklopdie der mathematischen Wissenschaften mit Einschluss ihrer Anwendungen

$49.99

Pathology of Asbestos-Associated Diseases

$199.99

Advances in the Base Force Element Method

$109.99

Computer-Aided Innovation (CAI)

$109.99

Globalgeschichten der deutschen Literatur

$89.99

Rough Set Theory: A True Landmark in Data Analysis

$129.00

Major Financial Institutions of Europe 1993

$74.99

Post-NAFTA North America

$39.99

Electromagnetic Radiation: Variational Methods, Waveguides and Accelerators

$69.99

Intersection Cohomology

$89.00

Free Energy Transduction and Biochemical Cycle Kinetics

$54.99

Industry 4.0 for the Built Environment

$279.99

UNIX transparent

$69.99

The Litani River, Lebanon: An Assessment and Current Challenges

$84.99

Numerical Methods for Bifurcation Problems and Large-Scale Dynamical Systems

$39.99

Economic Institutions in a Dynamic Society: Search for a New Frontier

$109.99

Prediction of Protein Secondary Structure

$169.99

Computational Collective Intelligence

$109.99

Gendered Policies in Europe

$84.99

Public-Key Cryptography PKC 2016

$39.99

Eine mediko-mechanische Abteilung, von Leichtverwundeten kostenlos hergestellt

$59.99

Class 1 Oxidoreductases V

$329.99

Beratungslehrer

$59.99

Improving Oral Health for the Elderly

$179.99

Expert SharePoint 2010 Practices

$54.99

Modernisierung und Folgelasten

$39.99

Gender-Rhetorik

$49.99

Pain & Passion

$109.99

Moonlighting Cell Stress Proteins in Microbial Infections

$169.99

Microcontrollers in Practice

$189.00

Lebenszykluskosten optimieren

$69.99

A Mindful Approach to Team Creativity and Collaboration in Organizations

$69.99

Transactions on Computational Collective Intelligence XXIX

$39.99

Der Blumenspiegel

$29.99

Fortschritte in der Me- und Automatisierungstechnik durch Informationstechnik

$59.99

Wings of Fire: The Poison Jungle (#13) (Hardcover)

$12.74

Mechanical Properties of Nanomaterials

$249.99

Smart Helicopter Rotors

$109.99