Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Farnesyltransferase Inhibitors in Cancer Therapy

Farnesyltransferase Inhibitors in Cancer Therapy

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781592590131
Condition
New
Product Description

With the explosion of research on genes capable of causing cancer, it has become clear that mutations in the GTPase, Ras, a major regulator of cell division, are found in about 30% of all human cancers, and that farnesylation, a lipid posttranslational modification of Ras, is required for its cancer-causing activity. In Farnesyltransferase Inhibitors in Cancer Therapy, cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farnesyltransferase inhibitors (FTIs) and geranylgeranyltransferase inhibitors (GGTIs) that can be used as anticancer drugs and in cardiovascular and parasitic therapy. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. The book also discusses the results from several phase I and II human clinical trials using a variety of FTIs, and demonstrates the design of hypothesis-driven clinical trials with proof-of-concept using biochemical endpoints. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific and medical aspects of farnesyltransferase inhibitors.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$129.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

$129.00
See Site In stock Visit Store

Similar Products

Foundational Problems in the Special Sciences

$109.99

Controlling & Management Review - Jahrgang 2017

$79.99

Fitness und Karriere

$59.99

Radiation Oncology for Pediatric CNS Tumors

$199.99

Logische und Methodische Grundlagen der Programm- und Systementwicklung

$37.99

Chinesische psychosomatische Medizin

$39.99

Akim Aliu: Dreamer (Original Graphic Memoir)

$11.24

The Afghan Patchwork State

$129.99

Survival and Revival in Sweden's Court and Monarchy, 17181930

$129.99

Flexible Query Answering Systems

$39.99

Mechanism and Theory in Food Chemistry

$169.99

Feedback Control

$119.99

85 Jahre Universittsklinik fr Dermatologie und Venerologie Zrich (19162001)

$59.99

Percutaneous Coronary Intervention for Chronic Total Occlusion

$179.99

Organisationale Metakompetenzen

$99.99

Bilanzieren nach Handels- und Steuerrecht, Teil 2

$69.99

Alzheimers and Parkinsons Diseases

$329.99

The Chinese Aspectual System

$179.99

Der deutsche Privatbankier

$69.99

Soziologie und Alter(n)

$59.99

Violence, Victimisation and Young People

$129.99

Wissenschaft frs Fernsehen

$39.99

Smart City wird Realitt

$44.99

Life Cycle Assessment of Natural Gas Vehicles

$39.99

Lasermedizin in der sthetischen Chirurgie

$69.99

Qualittsmanagement im Kundenservice

$49.99

Functional Illness of the Head and Neck

$129.99

Innovative kommunale Wirtschaftsfrderung

$44.99

A Critical Theory for the Anthropocene

$129.99

Der informelle Beteiligungskapitalmarkt

$59.99

XIth International Astronautical Congress Stockholm 1960

$84.99

Reducing CO2 Emissions

$54.99

The Managed Body

$59.99

Stimulation of Fracture Healing with Ultrasound

$54.99

Energieumsatz, Wirkungsgrad und Pulsfrequenzverhalten des Hundes beim Laufen auf der Tretbahn im Ver

$54.99

Computer Vision and Image Processing

$149.00

Visual Revelations

$54.99

Nitroarenes

$39.99

Muster der Reprsentation

$49.99

A Technical Manual for Parasitic Weed Research and Extension

$169.99