Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Farnesyltransferase Inhibitors in Cancer Therapy

Farnesyltransferase Inhibitors in Cancer Therapy

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781592590131
Condition
New
Product Description

With the explosion of research on genes capable of causing cancer, it has become clear that mutations in the GTPase, Ras, a major regulator of cell division, are found in about 30% of all human cancers, and that farnesylation, a lipid posttranslational modification of Ras, is required for its cancer-causing activity. In Farnesyltransferase Inhibitors in Cancer Therapy, cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farnesyltransferase inhibitors (FTIs) and geranylgeranyltransferase inhibitors (GGTIs) that can be used as anticancer drugs and in cardiovascular and parasitic therapy. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. The book also discusses the results from several phase I and II human clinical trials using a variety of FTIs, and demonstrates the design of hypothesis-driven clinical trials with proof-of-concept using biochemical endpoints. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific and medical aspects of farnesyltransferase inhibitors.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$129.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

$129.00
See Site In stock Visit Store

Similar Products

Drugs of Abuse, Immunity, and AIDS

$39.99

Management of Convergence Networks and Services

$109.99

Neurofeminism

$109.99

Mobile Strategy

$59.99

High Performance Memory Systems

$54.99

Die Geburt aus ethnomedizinischer Sicht

$69.99

Fortschritte der Hochpolymeren-Forschung

$39.99

Modulators, Mediators, and Specifiers in Brain Function

$39.99

Zwischenbetriebliche Kooperation mit mySAP.com

$49.99

Global Capital, Human Needs and Social Policies

$44.00

Kaiser Wilhelm I. und seine Zeit

$49.99

150 Jahre Gesetzgebung in Deutschland

$39.99

Renewable Energy Generation and Value Addition from Environmental Microfiber Pollution Through Advan

$149.00

Image Analysis and Recognition

$54.99

Buddy Readers: Level A (Single-Copy Set)

$17.99

Handbook for Online Learning Contexts: Digital, Mobile and Open

$249.99

Pearls of Glaucoma Management

$119.00

Store-operated Ca2+ entry (SOCE) pathways

$129.00

Chemie der Enzyme

$44.99

Influence of WTO and Global Dynamics on Trade Flows

$159.99

Hydrogen Materials Science and Chemistry of Metal Hydrides

$169.99

Migration and Social Remittances in a Global Europe

$119.99

E-Learning

$139.99

Programmieren mit R

$29.99

Economics of the Environment

$54.99

Biologically Inspired Design

$169.99

Trends, Techniques, and Problems in Theoretical Computer Science

$39.99

Exploring Sustainable Behavior Structure in Higher Education

$54.99

Widerstand gegen Groprojekte

$17.99

Archives, Accountability, and Democracy in the Digital Age

$54.99

Could You Ever Waddle with Penguins!?

$5.99

Bone: Crown of Horns

$9.74

Complex Cases in Structural Heart Intervention

$249.99

Gabler | MLP Berufs- und Karriere-Planer IT und e-business 2008 | 2009

$19.99

Cerebrovascular and Endovascular Neurosurgery

$139.99

Ultra High Pressure Treatment of Foods

$169.99

Critique of Pure Nature

$59.99

Cotton, Water, Salts and Soums

$169.99

Risk Assessment in Oral Health

$89.00

Real-Variable Theory of Musielak-Orlicz Hardy Spaces

$79.99