Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Telomeres and Telomerase in Aging, Disease, and Cancer

Telomeres and Telomerase in Aging, Disease, and Cancer

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9783540737087
Condition
New
Product Description

Twenty-five years after the disclosure of the telomeric DNA sequence and 22 years after the discovery of telomerase, it has become clear that telomeres and telomerase influence disease of human ageing including cancer. This book summarizes our current knowledge on the role of telomeres and telomerase in ageing, regeneration, and cancer with a special focus on ageing stem cells. Moreover, the book reviews current ef forts to target telomeres and telomerase for anticancer treatment or reg- erative therapies. 1. 1 Ageing The molecular analysis of ageing is an emerging research field that will have great impact on patients care, lifestyle, and on disease prevention in the human population worldwide. Major molecular mechanisms that influence the ageing process include (1) the accumulation of molecular damage affecting DNA and p- teins, (2) alterations in gene expression, including alterations in checkpoint responses, metabolic pathways, and developmental pathways, and (3) the decline in adult stem cell function. All these mechanisms lead to a decrease in organ main- nance and function, thus representing a major factor limiting the quality of life d- ing ageing. Moreover, the accumulation of molecular damage increases genetic alterations and the cancer risk during ageing. Indeed, increased age is the leading cause of cancer. Understanding the molecular basis of ageing will ultimately point to targets for novel therapies aiming to improve the function of cells and organs in the ageing organism, thus allowing increased vitality or what we think of as healthy ageing.

Available Colors
Available Sizes
1 Offer Price Range: $169.00 - $169.00
BEST PRICE

Single Product Purchase

$169.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$169.00 $169.00

$169.00
See Site In stock Visit Store

Similar Products

National Interests and European Integration

$54.99

Betriebswirtschaftliche Fragen zu Steuern, Finanzierung, Banken und Management

$99.99

Structural Sensitivity Analysis and Optimization 2

$129.00

Eradicating Energy Poverty

$129.99

Macrame Pattern Book- Includes Over 70 Knots and Repeat Patterns Plus Projects by Marchen Art

$22.99

Spherical Functions of Mathematical Geosciences

$299.99

Interprofessionalitt in der Tagesbetreuung

$59.99

Symmetry and Symmetry-Breaking in Semiconductors

$119.99

The Life and Death of a Treaty

$109.99

Advances in Spatial Econometrics

$169.99

Data-Driven Technology for Engineering Systems Health Management

$199.99

Rational Points on Algebraic Varieties

$129.00

Ladoga and Onego - Great European Lakes

$169.99

Der digitale Prototyp

$79.99

Probability Theory

$39.99

Determinism and Self-Organization of Human Perception and Performance

$199.99

Recent Developments in Acoustics

$279.99

The First Twelve Weeks of Gestation

$39.99

Living Otherwise

$49.99

Biological Adhesives

$169.00

New Trends in Distribution Logistics

$54.99

Design and Applications of Emerging Computer Systems

$169.99

Food Tourism in Asia

$199.99

Standard of Living

$169.99

Taiwanese Pilgrimage to China

$54.99

Diagnosis and Management of Polycystic Ovary Syndrome

$109.99

Glioblastoma:

$169.00

Water and Territory in Latin America

$84.99

Corporate Social Responsibility in Europe

$109.99

Internet Science

$54.99

Mary Anne Saves the Day: A Graphic Novel (The Baby-Sitters Club #3) (Hardcover)

$18.74

Essential Spectrum-based Fault Localization

$109.99

Pdagogik fr Psychotherapeutinnen und Psychotherapeuten

$19.99

Handbuch Medienerziehung im Kindergarten

$64.99

Textbook of Echocardiography for Intensivists and Emergency Physicians

$169.99

Protein Design and the Development of New Therapeutics and Vaccines

$39.99

Computational Intelligence Methods for Bioinformatics and Biostatistics

$54.99

Mobility Modeling for Vehicular Communication Networks

$54.99

Proceedings of 2023 Chinese Intelligent Automation Conference

$329.99

Behavioral Approaches to Chronic Disease in Adolescence

$109.99