Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Enzyme- and Transporter-Based Drug-Drug Interactions

Enzyme- and Transporter-Based Drug-Drug Interactions

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781441908407
Condition
New
Product Description

Germination of the thought of "Enzymatic- and Transporter-Based Drug-Drug Interactions: Progress and Future Challenges" Proceedings came about as part of the annual meeting of The American Association of Pharmaceutical Scientists (AAPS) that was held in San Diego in November of 2007. The attendance of workshop by more than 250 pharmaceutical scientists reflected the increased interest in the area of drug-drug interactions (DDIs), the greater focus of PhRMA, academia, and regulatory agencies, and the rapid pace of growth in knowledge. One of the aims of the workshop was to address the progress made in quantitatively predicting enzyme- and transporter-based DDIs as well as highlighted areas where such predictions are poor or areas that remain challenging for the future. Because of the serious clinical implications, initiatives have arisen from the FDA (http://www.fda.gov/cber/gdlns/interactstud.htm) to highlight the importance of enzyme- and transporter-based DDIs. During the past ten to fifteen years, we have come to realize that transporters, in addition to enzymes, play a vital role in drug elimination. Such insight has been possible because of the continued growth in PK-ADME (pharmacokinetics-absorption-distribution-metabolism-excretion) knowledge, fueled by further advances in molecular biology, greater availability of human tissues, and the development of additional and sophisticated model systems and sensitive assay methods for studying drug metabolism and transport in vitro and in vivo. This has sparked an in-depth probing into mechanisms surrounding DDIs, resulting from ligand-induced changes in nuclear receptors, as well as alterations in transporter and enzyme expression and function. Despite such advances, the in vitro and in vivo study of drug interactions and the integration of various data sets remain challenging. Therefore, it has become apparent that a proceeding that serves to encapsulate current strategies, approaches, methods and applications is necessary. As Editors, we have assembled a number of opinion leaders and asked them to contribute chapters surrounding these issues. Many of these are the original Workshop speakers whereas others had been selected specially to contribute on topics related to basic and applied information that had not been covered in other reference texts on DDI. The resulting tome, entitled Enzyme- and Transporter-Based Drug Interactions: Progress and Future Challenges, comprises of four sections. Twenty-eight chapters covering various topics and perspectives related to the subject of metabolic and transporter-based drug-drug interactions are presented.

Available Colors
Available Sizes
1 Offer Price Range: $169.00 - $169.00
BEST PRICE

Single Product Purchase

$169.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$169.00 $169.00

$169.00
See Site In stock Visit Store

Similar Products

Der Bohrlochneigungsmesser der Gesellschaft fr nautische Instrumente G. m. b. H

$54.99

African American Settlements in West Africa

$54.99

Kenneth Boulding

$84.99

Water Development and Poverty Reduction

$84.99

Dance Pedagogy and Education in China

$39.99

Preclinical Evaluation of Antimicrobial Nanodrugs

$109.99

The Challenge of Late Industrialization

$130.00

PET-CT

$199.99

Cellular Automaton Modeling of Biological Pattern Formation

$149.00

Renaturierung von kosystemen in Mitteleuropa

$79.99

Delay Fault Testing for VLSI Circuits

$169.99

Of Poles and Zeros

$109.99

Avian Migration

$329.99

Finanzmathematik in der Bankpraxis

$79.99

Phenomenology of Life - From the Animal Soul to the Human Mind

$169.99

Grade Models and Methods for Data Analysis

$169.00

Analytical and Stochastic Modeling Techniques and Applications

$39.99

Balanced Silverman Games on General Discrete Sets

$54.99

Introductory Statistical Inference with the Likelihood Function

$54.99

Business and Society

$169.99

Der verdrngte Finanznotstand

$139.00

Handbook of Applied Teaching and Learning in Social Work Management Education

$159.99

The Intersection of Trauma and Disaster Behavioral Health

$109.99

Robust and Optimal Control

$129.00

The Genetic Markers of Human Immunoglobulins

$109.99

Advances in Mechanical and Electronic Engineering

$219.99

Ophiolite Genesis and Evolution of the Oceanic Lithosphere

$54.99

All the Broken Pieces

$6.74

Digital Terrestrial Broadcasting Networks

$109.99

Statistical Mechanics of Superconductivity

$89.99

Botanical Leads for Drug Discovery

$169.99

Soviet Maser Research

$54.99

Bargaining over Time Allocation

$54.99

Orthogonal Polynomials for Exponential Weights

$39.99

Weltliteratur

$74.99

Historias de xito within Mexican Communities

$54.99

Technical Thermodynamics Workbook for Engineers

$109.99

The Digital Journey of Banking and Insurance, Volume III

$44.99

Proceedings of the 52nd American Solar Energy Society National Solar Conference 2023

$219.00

Pediatric Critical Care Medicine

$109.00