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Bedeutung der Zell-Matrix-Interaktion fr die linksventrikulre Hypertrophie

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Brand
Springer Nature
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N/A
Part Number
0
GTIN
9783798512429
Condition
New
Product Description

Dieses Buch versteht sich als eine Ergnzung zum bereits vorhandenen Wissen ber die zellulren und molekularen Mechanismen der linksventrikulren Hypertrophie. Die vorgestellten neuen Aspekte beruhen auf den Ergebnissen aus der Wundheilungsforschung, hier besonders die Interaktion zwischen dem bindegewebigen Gerst des Herzens und den Fibroblasten, eine Abhngigkeit, die bisher wenig beleuchtet wurde. Eine besondere Bedeutung bei der linksventrikulren Hypertrophie scheint das Adhsionsprotein Osteopontin zu haben, das bei der Hypertrophie verstrkt exprimiert wird. Dieses Protein beeinflut Fibroblastenfunktionen an einer besonderen zellbiologischen Schnittstelle, deren Bedeutung fr kardiale pathophysiologische Prozesse zustzliche Beachtung verdient.

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