Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Stearoyl-CoA Desaturase Genes in Lipid Metabolism

Stearoyl-CoA Desaturase Genes in Lipid Metabolism

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9781461479680
Condition
New
Product Description

Obesity and diabetes develop as a complex result of genetic, metabolic and environmental factors and are characterized by increased lipogenesis and lipid accumulation in many tissues. Stearoyl-CoA desaturase (SCD) genes are a critical regulator of lipogenesis and catalyzes the synthesis of monounsaturated fatty acids (MUFA), mainly oleoyl- (18:1n9) and palmitoleoyl-CoA (16:1n7). These MUFAs are the major fatty acid substrates for the synthesis of triglycerides, cholesterol esters, wax esters and membrane phospholipids. There are 4 SCD isoforms (SCD1-4) in mice and two (hSCD1 and hSCD5) expressed in humans. At first glance, stearoyl-CoA desaturase enzyme would be considered a housekeeping enzyme because it synthesizes oleate a well-known fatty acid that is abundant in many dietary sources. However numerous studies have shown that SCD is a very highly regulated enzyme that features in so many physiological processes ranging from fat differentiation, carbohydrate and fat metabolism, inflammation and cancer. The editors studies using stearoyl-CoA desaturase knockout (SCD1-/-) mice and studies of other investigators using pharmacological approaches to reduce SCD1 expression in mouse tissues have all established that the expression of SCD1 gene isoform represents a key step in partitioning of lipids between storage and oxidation. High SCD expression favors fat storage leading to obesity while reduced SCD expression favors fat burning and leanness. Although these studies clearly illustrated that SCD1 expression is involved in the development of obesity and insulin resistance, questions remain in the elucidation of the mechanisms involved and role of SCD1. This book includes chapters by leading researchers on SCD Genes in the brain, heart, muscle, liver metabolism, Colitis, and more.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$129.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

$129.00
See Site In stock Visit Store

Similar Products

Die Verdammten der Stadt

$64.99

Environmental Management

$54.99

Legal barriers to the energy modernisation of dwellings occupied by low-income tenants and opportuni

$129.99

Combinatorial Testing in Cloud Computing

$39.99

The Ionotropic Glutamate Receptors

$169.99

Three Concepts of Time

$54.99

Practical Aspects of Computational Chemistry III

$84.99

Catalogue of Books and Periodicals on International Law and Diplomatic History

$54.99

Communications, Signal Processing, and Systems

$379.99

Recent Advances in Reliability and Quality in Design

$219.99

Die uere Sekretion der Verdauungsdrsen

$59.99

Design Research in Information Systems

$79.99

Welt im Wandel: Neue Strukturen globaler Umweltpolitik

$59.99

Recent Advances in Civil Engineering

$279.99

Verkehrshaftungsversicherungen

$69.99

Obst, Sdfrchte (einschlielich Agrumen) und Mohn

$59.99

New Free Trade Agreements in the Asia-Pacific

$109.99

Waste to Energy

$169.99

Performative Figures of Queer Masculinity

$109.99

Nanotechnology in Construction

$379.99

First Light in the Universe

$99.00

Pathology of the Eye

$74.99

UN Robust Peacekeeping

$109.99

The Practice of Lending

$84.99

Electron Transport in Nanosystems

$169.00

Unternehmensethik fr den Kulturbetrieb

$44.99

Eye Tracking

$219.99

Energieverbrauch und Einsparung in Gewerbe, Handel und Dienstleistung

$59.99

Managing the Transition to a Circular Economy

$37.99

Tipps und Tricks fr den Augenarzt

$69.99

Competition for Public Transport Services

$109.99

Tod und Gesellschaft

$69.99

Optionsbewertung und Portfolio-Optimierung

$44.99

Practical Aspects of Declarative Languages

$39.99

ICPT 91

$169.00

Mass Customization

$109.99

Modeling Digital Switching Circuits with Linear Algebra

$29.99

The Emerging Digital Economy

$84.99

Entangled State Representations in Quantum Optics

$169.99

Particles and Policy

$54.95