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Einbau und Faltung von -Fass Membranproteinen in Bakterien

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Product Details

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9783658126537
Condition
New
Product Description

Lisa Gerlach beschftigt sich mit der Faltung von Membranproteinen einem komplexen Prozess, der mehrere Faltungsfaktoren erfordert. Sie beschreibt die Funktion des Membran-gebundenen BamB als Faltungshelferprotein fr Auenmembranproteine (OMPs) in Gram-negativen Bakterien und seine Bedeutung fr den Membranaufbau. Dazu isoliert sie BamB aus Escherichia coli in denaturierter Form. Ausgewhlte biochemische und biophysikalische Methoden demonstrieren die Renaturierung von BamB in vorprparierte Lipid-Modellmembranen und zeigen die Funktion von BamB auf, die Faltung und Insertion des OmpA zu erleichtern.

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