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Einfhrung in die BIOinformatik
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Dieses Lehrbuch bildet eine Brcke von der Biologie zur Bioinformatik. Die Methoden fr die Erstellung klassischer Stammbume werden zunchst resmiert, bevor DNA- und Protein-Sequenzen als digitalisierbare Merkmale den bergang zu den Prinzipien der Bioinformatik ermglichen. Der Vergleich von Sequenzen in Alignments bildet die Grundlage fr molekulare Homologien, ermglicht die Sequenzsuche in Datenbanken und erlaubt die Ableitung von molekularen Phylogenien. Die wesentlichen Prinzipien fr moderne Anwendungen der Bioinformatik, wie Methoden von Transcriptomics und die Vorhersage von Protein-Strukturen, finden sich im letzten Kapitel. Aufgaben und ihre Lsungen ermuntern zur Anwendung der BIOinformatik und motivieren zu eigenen Fragestellungen.
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