Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Human Ring Chromosomes

Human Ring Chromosomes

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9783031475290
Condition
New
Product Description

This book presents chromosome-wise clinical cases following an evidence-based protocol, in addition to providing the scientific background on the mechanisms of human ring chromosome (RC) formation. Presence of RCs in a genome can lead to several rare genetic diseases. This book, edited by the leading experts Prof. Peining Li and Prof. Thomas Liehr, is the first comprehensive book on this topic. Over the past 60 years, banding cytogenetics, fluorescence in situ hybridization, chromosome microarray analysis, and whole genome sequencing have been used to diagnose cases with a RC. Ring syndrome of sever growth retardation and variable intellectual disability has been considered a common clinical feature for all RCs. Clinical heterogeneity of chromosome-specific deletion and duplication syndromes, gene-related organ and tissue defects, cancer predisposition to different types of tumors, and reproduction failure has been reported in the literature. However, the cases of RCs reportedin the literature account for less than 1% of its real occurrence. Current diagnostic practice lacks laboratory standards for analyzing cellular behavior and genomic imbalances of RCs to evaluate its compound effects on patients. The under-representation of clinical cases and the lack of comprehensive diagnostic analysis make challenging to establish accurate clinico-cytogenomic correlations. Given recent advances in genomic technology and organized efforts from peer experts, standardized cytogenomic diagnosis and evidence-based clinical management could be envisioned for all patients with RCs. Furthermore, supernumerary small ring chromosomes and the patients perspective are addressedthe latter by including family stories of RC-carrier relatives. Acquired RCs in various cancers are also discussed, as well as the potential role of RCs in research applications like iPSC cellular modeling and genomic editing. This book is a valuable reference for clinical geneticists, personnel in cytogenetics and molecular genetics laboratories, genetic counselors, and researchers in related fields.

Available Colors
Available Sizes
1 Offer Price Range: $109.00 - $109.00
BEST PRICE

Single Product Purchase

$109.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$109.00 $109.00

$109.00
See Site In stock Visit Store

Similar Products

Unternehmenswertsteigerung durch strategische Desinvestitionen

$69.99

Critical Planning and Design

$159.99

Enterprise Ontology

$219.99

The Ethological Roots of Culture

$54.99

National Geographic Kids Readers: Rocks & Minerals

$4.46

Vorlesungen ber Orthogonalreihen

$54.99

Problems of Normativity, Rules and Rule-Following

$84.99

Halbleiterbauelemente der Hochfrequenztechnik

$69.99

Computational Physics

$39.99

Genotoxicity Assessment

$199.99

Capital Market Equilibria

$129.00

Desmond Cole Collection Grades 1-3 (4 books)

$16.00

Soviet Women on the Frontline in the Second World War

$129.99

Literary Minstrelsy, 1770-1830

$54.99

Humanitarian Intervention and the Responsibility to Protect

$44.99

Biophysik der Ernhrung

$39.99

Surface Effects in Solid Mechanics

$109.99

Stacey's Mistake: A Graphic Novel (The Baby-Sitters Club #14)

$9.74

Extreme Hydrological Events: New Concepts for Security

$129.00

VEGF Signaling

$84.99

General Principles of Tumor Immunotherapy

$219.99

Basic Concepts of Molecular Pathology

$159.99

Sicherheit als professionelle Dienstleistung und Mythos

$49.99

Land and Labor in Europe in the Twentieth Century

$39.99

Exploring the Limits of the Human through Science Fiction

$54.99

Stupid as a Fish?

$44.99

Womens Rights, Racial Integration, and Education from 18501920

$54.99

Corporate Financial Resilience

$49.99

Statistical Handbook of United Kingdom Agriculture

$54.99

Hermeneutische Knste

$69.99

Strafvollstreckung

$29.99

Concrete Structures Under Projectile Impact

$219.99

Achtsamkeit in Arbeitswelten

$49.99

Linear Selection Indices in Modern Plant Breeding

$59.99

Lundberg Approximations for Compound Distributions with Insurance Applications

$54.99

Irregularity in Graphs

$79.99

History of Original Ideas and Basic Discoveries in Particle Physics

$259.00

Innovations in Biomedical Engineering

$169.99

Atmospheric Nuclear Tests

$219.99

The Collected Works of Mihaly Csikszentmihalyi

$109.99