Promotes healthy cellular immune response to support innate immunity. The PureResponse formula Innate Immune Support is designed to promote cell- mediated immune response, including NK cell and macrophage activity. Innate Immune Support may be indicated for enhancement of natural defenses and mucosal health. Astragalus contains a variety of active constituents, including saponins and flavonoids, that contribute to its long tradition of immune and cytokine balance support. In vitro and animal studies suggest that astragalus supports NK cell activity, as well as IgA and IgG levels in serum, key antibodies that play a critical role in mucosal immune defense. The formula also includes clinically researched andrographis extract standardized for andrographolide and other bioactive diterpene lactones. Each batch is biologically standardized using the lipoxygenase inhibition assay to ensure efficacy. In a randomized, double-blind, placebo-controlled study, supplementation with 200 mg of AP-Bio Andrographis for five days promoted immune function and supported respiratory comfort. In vitro assays suggest it helps modulate IL-1, IL-6 and MCP-1 to support macrophage function. Reishi mushroom offers a rich source of polysaccharides to promote cell-mediated immunity. The formula includes both reishi mushroom extract and a unique, highly-purified, reishi mushroom-derived beta 1,3/1,6-D glucan extract.Part of the PureResponse Immune Protocol for healthy immune balance and function Contains a blend of astragalus, biologically standardized andrographis, and reishi mushroom beta glucans, including highly purified yeast-free beta 1,3/1,6-D glucan and lectins derived from reishi mushroomPromotes respiratory, gastrointestinal and immune functionDietary ConsiderationsGluten Free Non-GMOServing Size: 1 CapsuleServings Per Container: 60Amount Per ServingAstragalus (Astragalus membranaceus) extract (root) 240 mg AP-Bio Andrographis (Andrographis paniculata) extract (leaf) (standardized to contain 31.5% andrographolide) 200 mg Mushroom beta glucan (from reishi (Ganoderma lucidum) extract (mycelia)) (standardized to contain 70% beta 1,3/1,6 glucan) 100 mg Reishi (Ganoderma lucidum) extract (fruiting body) 100 mgOther IngredientsVegetarian capsule (cellulose, water), water, Hypoallergenic plant fiber (cellulose)Suggested UseAs a dietary supplement, take 1 capsule, 1-2 times daily between meals or as directed by a health professional Certified Gluten free. Non-GMO & Hypoallergenic.WarningIf you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use. Keep out of the reach of children. Store in a cool, dry place.