SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient normal aches and pains resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the maintenance of a positive mood. Supports Nervous System and Joint Health Stabilized SAMe, Capsule Form No Enteric Coating Needed Dietary Considerations Wheat Free Dairy/ Milk Free Gluten Free Vegetarian Soy Free Vegan Egg Free Shellfish Free Fish Free Tree Nut Free Serving Size: 1 Vegetable Capsule Servings Per Container: 60 Amount Per Serving SAMe (S-Adenosyl-L-Methionine) (from S-Adenosyl-L-Methionine Disulfate Tosylate) Other Ingredients: Hypromellose (cellulose capsule), Microcrystalline Cellulose, Silicon Dioxide, Stearic Acid (vegetable source) Take 1 capsule 2 to 4 times daily, or as directed by your healthcare practitioner. Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens. Natural color variation may occur in this product. Cautions/Interactions: Theoretically, SAMe could increase the effects and adverse effects of products that increase serotonin levels, including 5-hydroxytryptophan (5-HTP), Hawaiian baby woodrose, L-tryptophan, and St. John's wort. In addition, SAMe may interact with MAO inhibitors, L-Dopa, antidepressants and other serotonergic drugs. Consult healthcare practitioner if pregnant/nursing, taking medication, or have a medical condition, especially bipolar or anxiety disorders.