Progesterone therapy is used to relieve symptoms of both PMS (when progesterone levels are low and/or estrogen is dominant) and menopause (when both estrogen and progesterone decrease). Suggested Use: Gently rub 1/8 to 1/2 tsp. on clean skin. Apply to belly, thighs, or wrists twice daily. Use 1-2 weeks prior to menstruation each month. Non-menstruating women use any 3 weeks each month. Best results with regular use as directed. Supplement Facts: Aloe barbadenis leaf extract, C12-12, alkyl benzoate, stearic acid, Mexican yam concentrat, glyceryl stearate, PEG-100 stearate, glycerin, octyl palmitate, water, progesterone, burdock root extract, Asian ginseng root extract, chaste tree berry fruit extract, chamomile flower extract, safflower seed oil, jojoba seed oil, tochopheryl acetate, cetyl alcohol, dimethicone, carbomer, diazolidinyl ura, iodopropynyl, butylcarbamate, tetrasodium EDTA, triethanolamine, fragrance.