Activated folate, vitamin B12 and B6 combination Folate 5,000 Plus provides 5,000 mcg of folate as 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate, combined with activated vitamin B12 and B6. Optimal levels of these B vitamins have been associated with cellular, cardiovascular, neurological and emotional health. Activated B vitamins provide methyl groups to support healthy methylation, a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, hormone and neurotransmitter production, and energy metabolism. Research suggests that B vitamins help maintain a healthy nervous system function. In a randomized controlled study, a combination of methylfolate, methycobalamin, and pyridoxal-5-phosphate promoted healthy epidermal nerve fiber density and nerve comfort. These vitamins also enhance healthy endothelial function and play a vital role in the metabolism of homocysteine. 5,000 mcg of activated folate per capsule Combination of activated B vitamins Made with hypoallergenic, vegan ingredientsDietary ConsiderationsGluten Free Non-GMOServing Size:1 Vegetable CapsuleServings Per Container:60Amount Per Serving % Daily ValueVitamin B6 (as pyridoxal 5' phosphate (activated B6)) 25 mg 1471% Folate (as Quatrefolic (6S)-5-Methyltetrahydrofolic acid, glucosamine salt) (5,000 mcg 5-MTHF) DFE 8333 mcg 2083% Vitamin B12 (as methylcobalamin) 1000 mcg 41667%Other Ingredientshypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water)Suggested UseAs a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.WarningIf you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use. Keep out of the reach of children. Store sealed in a cool, dry place. Tamper Resistant:Use only if safety seal is in tact.