Compare Prices | Create Shopping Lists with Price Drop Alerts | Set Coupons, Promo Codes & Sales Alerts | Get Access to Exclusive Deals and Much More... All in One Place | Read all about it here

Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications

Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications

Brand
Springer Nature
Manufacturer
N/A
Part Number
0
GTIN
9789400773592
Condition
New
Product Description

The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic anhydrase (CA) has exploded in recent years with the identification of new families and isoforms. The CAs are metalloenzymes which are comprised of 5 structurally different families: the alpha, beta, gamma, and delta, and epsilon classes. The alpha class is found primarily in animals with several isoforms associated with human disease. The beta CAs are expressed primarily in plants and are the most divergent. The gamma CAs are the most ancient. These are structurally related to the beta CAs, but have a mechanism more similar to the alpha CAs. The delta CAs are found in marine algae and diflagellates. The epsilon class is found in prokaryotes in which it is part of the carboxysome shell perhaps supplying RuBisCO with CO2 for carbon fixation. With the excitement surrounding the discovery of disease-related CAs, scientists have redoubled their efforts to better understand structure-function relationships, to design high affinity, isotype-specific inhibitors, and to delineate signaling systems that play regulatory roles over expression and activity. We have designed the book to cover basic information of mechanism, structure, and function of the CA families. The authors included in this book bring to light the newest data with regard to the role of CA in physiology and pathology, across phylums, and in unique environmental niches.

Available Colors
Available Sizes
1 Offer Price Range: $129.00 - $129.00
BEST PRICE

Single Product Purchase

$129.00
@ Link.springer.com     BUY Now

Price Comparison

Seller Contact Seller List Price On Sale Shipping Best Promo Final Price Volume Discount Financing Availability Seller's Page
BEST PRICE
1 Product Purchase
@ Link.springer.com
Contact Store Call Store Contact Support
$129.00 $129.00

$129.00
See Site In stock Visit Store

Similar Products

Psychopathology in Adolescents and Adults with Autism Spectrum Disorders

$179.99

Classical and Quantum Physics

$109.99

Certified Ethical Hacker (CEH) Preparation Guide

$64.99

Women and Adjustment Policies in the Third World

$109.99

Universities in the Knowledge Society

$179.99

On Arms Control

$44.99

U.S. Strategy Against Global Terrorism

$54.99

The US Strategic Pivot to Asia and Cross-Strait Relations

$54.99

Engaging Learners Through Emerging Technologies

$39.99

South Africa's Renegade Reels

$54.99

Kommunalpolitik in der Bundesrepublik

$19.99

Black Women's Wellness: Your "I've Got This!" Guide to Health, Sex, and Phenomenal Living by Melody T. McCloud Md

$26.99

Human-Computer Interaction. Theories, Methods, and Tools

$109.99

Deutsche Strophenformen des Mittelalters

$59.99

Combinatorial Library

$129.00

Komplikationen in der Unfallchirurgie

$69.99

The Matrix of Insanity in Modern Criminal Law

$54.99

The Transnational Fantasies of Guillermo del Toro

$139.99

Test Policy and the Politics of Opportunity Allocation: The Workplace and the Law

$109.99

Spiel, Zufall und Kommerz

$19.99

Steine und Steinbrche im Alten gypten

$74.99

Childrens Images of Identity

$49.99

Schalentheorie

$29.99

Mathematische Lsungsverfahren fr planare Standortprobleme

$59.99

Child Rights to Guardianship

$109.00

The Christian Philosophy of William Temple

$109.99

Fluid Flow, Heat Transfer and Boiling in Micro-Channels

$169.99

Interculturality Between East and West

$129.99

A Moral Defense of Recreational Drug Use

$54.99

Gold-Bergwerke in Sumatra, 16801683

$49.99

When Money Changes Society

$54.99

Integration von Forschung und Entwicklung in die unternehmerische Planung und Steuerung

$59.99

On-Site Drug Testing

$199.99

Accelerated Silverlight 3

$44.99

Narrative Organizations

$39.99

Ergebnisse der Exakten Naturwissenschaften

$59.99

Negotiating Childhoods

$79.99

Narratives of Enclosure in Detective Fiction

$99.99

Public Services in EU Trade and Investment Agreements

$109.99

Algebraic and Analytic Microlocal Analysis

$249.99