Estriol Natural Balancing Cream features the same Vitamin-E-rich formula as Emerita's Pro-Gest Cream, with estriol instead of progesterone.Each ounce of Estriol Cream contains 18 mg of USP Estriol, 0.75 mg of estriol per 1/4 tsp of cream. Massage 1/4 tsp (about a dime-sized dollop) into your skin twice daily. Try wrists, arms, thighs, tummy - whatever you like.This tube of Estriol Cream contains approximately 84 1/4 tsp-applications. Great used on its own or in combination with Pro-Gest Cream. Contains no parabens, mineral oil, petroleum or animal anything. And Emerita products are never tested on animals.INGREDIENTS: Water, Tocopheryl Acetate (Vit E), Aloe Barbadensis (Aloe Vera) Leaf Juice, Carthamus Tinctorius (Hybrid Safflower) Seed Oil, Panthenol, Glycerin, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Glyceryl Stearate, Cetyl Alcohol, Stearic Acid, Sodium Behenoyl Lactylate, USP Estriol, Carbomer, Potassium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Sorbic AcidSuggested Use: Massage 1/4 tsp (about a dime-sized dollop) into your skin twice daily. Try wrists, arms, thighs, tummy--whatever you like.As with any product, if you experience irritation or discomfort, discontinue use and consult a licensed health care practitioner. This bottle is sealed for your protection.